29 results found
    1. Developmental Biology

    Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

    Naokazu Inoue et al.
    Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Improving oligo-conjugated antibody signal in multimodal single-cell analysis

    Terkild B Buus et al.
    Oligo-conjugated antibodies are a powerful tool but require thorough optimization to reduce background signal, increase sensitivity, and reduce sequencing costs.
    1. Neuroscience

    Amphetamine reduces reward encoding and stabilizes neural dynamics in rat anterior cingulate cortex

    Saeedeh Hashemnia et al.
    Amphetamine reduces reward signaling by neurons in rat prefrontal cortex, but increases the stability of population dynamics, which account for animals’ increased task engagement, despite reduced reward motivation.
    1. Cell Biology
    2. Developmental Biology

    TMEM95 is a sperm membrane protein essential for mammalian fertilization

    Ismael Lamas-Toranzo et al.
    TMEM95, a protein localized to the sperm acrosome cap, is essential for fertilization.
    1. Neuroscience

    The hippocampus encodes delay and value information during delay-discounting decision making

    Akira Masuda et al.
    Two distinct subpopulations of CA1 neurons that increased or decreased their firing rate during delay were identified, suggesting that they have distinct roles in the valuation process in the hippocampus.
    1. Neuroscience

    A multilayer circuit architecture for the generation of distinct locomotor behaviors in Drosophila

    Aref Arzan Zarin et al.
    Generation of a premotor/motor neuron comprehensive TEM reconstruction, functional optogenetics, and recurrent network modeling reveals different phase relationships among a subset of Drosophila motor neurons in forward versus backward locomotion.
    1. Ecology

    Biophysical and physiological processes causing oxygen loss from coral reefs

    Cynthia B Silveira et al.
    Coral reef heterotrophic bacteria and fleshy macroalgae cause oxygen loss from reef systems through microbial biomass accumulation and ebullition from algae surfaces.
    1. Neuroscience

    Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition

    Ambra Masuzzo et al.
    The universal bacteria cell wall component peptidoglycan impacts the egg-laying behavior of infected Drosophila females by directly modulating the activity of few brain octopaminergic neurons.
    1. Ecology

    Adaptive thermal plasticity enhances sperm and egg performance in a model insect

    Ramakrishnan Vasudeva et al.
    Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.
    1. Neuroscience

    Neuroanatomy of a hydrothermal vent shrimp provides insights into the evolution of crustacean integrative brain centers

    Julia Machon et al.
    A neuroanatomical analysis of Rimicaris exoculata provides insights into these animal’s brain architecture to illustrate possible adaptations to the hydrothermal vent habitat with its extreme physicochemical conditions.

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