29 results found
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Improving oligo-conjugated antibody signal in multimodal single-cell analysis

    Terkild B Buus et al.
    Oligo-conjugated antibodies are a powerful tool but require thorough optimization to reduce background signal, increase sensitivity, and reduce sequencing costs.
    1. Physics of Living Systems

    Rheotaxis facilitates upstream navigation of mammalian sperm cells

    Vasily Kantsler et al.
    Mammalian sperm subject to shear flow swim in upstream spirals along the walls bounding such flows, thereby demonstrating a robust mechanism for upstream navigation to the ovum.
    1. Computational and Systems Biology
    2. Ecology

    Data-driven identification of potential Zika virus vectors

    Michelle V Evans et al.
    Data-driven methods predict over 35 mosquitoes are potential vectors of Zika virus, suggesting a larger geographic area and a greater human population is at risk of infection.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases

    Sofia Battaglia et al.
    In vivo and in vitro elongation factor-RNA interaction data provide a missing link in understanding how processive elongation complexes are formed on active genes and disassembled at the end of genes.
    1. Cell Biology
    2. Developmental Biology

    TMEM95 is a sperm membrane protein essential for mammalian fertilization

    Ismael Lamas-Toranzo et al.
    TMEM95, a protein localized to the sperm acrosome cap, is essential for fertilization.
    1. Ecology

    Biophysical and physiological processes causing oxygen loss from coral reefs

    Cynthia B Silveira et al.
    Coral reef heterotrophic bacteria and fleshy macroalgae cause oxygen loss from reef systems through microbial biomass accumulation and ebullition from algae surfaces.
    1. Genetics and Genomics

    Quiescence unveils a novel mutational force in fission yeast

    Serge Gangloff et al.
    The quiescence-driven mutational landscape reveals replication-independent mutagenesis as a novel evolutionary force.
    1. Computational and Systems Biology
    2. Ecology

    Trade-off shapes diversity in eco-evolutionary dynamics

    Farnoush Farahpour et al.
    In a minimalistic, generic model of competitive communities in which evolution is constrained by life-history trade-offs, stable biodiversity emerges with species adapted to different functional niches.
    1. Ecology

    Adaptive thermal plasticity enhances sperm and egg performance in a model insect

    Ramakrishnan Vasudeva et al.
    Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.
    1. Neuroscience

    A multilayer circuit architecture for the generation of distinct locomotor behaviors in Drosophila

    Aref Arzan Zarin et al.
    Generation of a premotor/motor neuron comprehensive TEM reconstruction, functional optogenetics, and recurrent network modeling reveals different phase relationships among a subset of Drosophila motor neurons in forward versus backward locomotion.

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