1,478 results found
    1. Cancer Biology
    2. Human Biology and Medicine

    Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

    Haley Hieronymus et al.
    The percentage of a tumor’s genome with alterations in copy number is correlated with increased mortality across a range of tumor types and can be measured using a clinically approved sequencing assay.
    1. Cell Biology

    Cyclin-dependent kinase control of motile ciliogenesis

    Eszter K Vladar et al.
    Cyclin-dependentkinase 2 (Cdk2), the master regulator of S phase events during the cell cycle, controls the earliest step in the motile ciliogenesis pathway in quiescent multiciliatedairway epithelial cells.
    1. Developmental Biology

    An intrinsic cell cycle timer terminates limb bud outgrowth

    Joseph Pickering et al.
    Size control in limbs is an intrinsically determined process.
    1. Cell Biology

    PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN

    Andrew Michael Sydor et al.
    The previously uncharacterized protein PPP1R35 is a novel centriolar luminal protein critical for centriole elongation by acting in a complex with microcephaly protein RTTN.
    1. Cancer Biology
    2. Cell Biology

    Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

    Giulia Bertolin et al.
    AurkA is imported into mitochondria at interphase, and it induces organelle elongation and enhances ATP production when over-expressed.
    1. Neuroscience

    Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing

    Arnaud Pautrat et al.
    The subthalamic nucleus is linked to a nociceptive network and involved in nociceptive processing and perception.
    1. Neuroscience

    BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior

    Kristen R Maynard et al.
    Brain-derived neurotrophic factor signaling plays a causal role in female-typical social behavior and modulates oxytocin neuron gene expression.
    1. Evolutionary Biology

    Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

    Fabien Duveau et al.
    The impact of changing gene expression noise on fitness reveals beneficial or deleterious effects in a stable environment depending how close the average expression level is to the fitness optimum.
    1. Developmental Biology
    2. Neuroscience

    MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

    Stephen R Tymanskyj et al.
    An under-studied microtubule-associated protein is found to regulate axon growth and branching by modulating microtubule-based organelle transport through its dual interactions with microtubules and the conventional kinesin motor.

Refine your results by:

Type
Research categories