Browse the search results

Page 2 of 3
    1. Stem Cells and Regenerative Medicine

    Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging

    Jacqueline A Larouche, Mahir Mohiuddin ... Carlos A Aguilar
    Muscle stem cells locally respond to perturbations of motor neurons and the neuromuscular junction.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans

    Gurmeet Kaur, Lakshminarayan M Iyer ... L Aravind
    Prokaryotic TRADD-N and Death-like adaptor domains in diverse predicted apoptosis and immune systems from multicellular prokaryotes and metazoans indicate the common origin of key apoptosis mechanisms required for the stabilization of multicellularity.
    1. Developmental Biology
    2. Neuroscience

    Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain

    Kathryn C Allaway, William Muñoz ... Gordon Fishell
    Cholinergic populations with distinct cellular birthdates innervate deep versus superficial layers of the cortex with exquisite specificity.
    1. Neuroscience

    Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

    Matthew Grove, Hyunkyoung Lee ... Young-Jin Son
    YAP and TAZ, potent concoproteins and therapeutic targets in cancer therapy, are essential for Schwann cells to support peripheral nerve regeneration.
    1. Neuroscience

    A Toll-receptor map underlies structural brain plasticity

    Guiyi Li, Manuel G Forero ... Alicia Hidalgo
    Structural brain plasticity is encoded in the topographic distribution of Toll receptors and their ability to switch between alternative signalling outcomes, thus translating diverse sensory experience into structural change.
    1. Neuroscience

    The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation

    Brandon Podyma, Dove-Anna Johnson ... Ali Deniz Güler
    A novel neurotrophin signaling axis underpins a behavioral response to food scarcity.
    1. Cell Biology
    2. Neuroscience

    Neurotrophins induce fission of mitochondria along embryonic sensory axons

    Lorena Armijo-Weingart, Andrea Ketschek ... Gianluca Gallo
    Induction of the fission of mitochondria-populating sensory axons is shown to be a novel biological action of neurotrophins.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor

    Anastasiia Stratiievska, Sara Nelson ... Sharona E Gordon
    A dual-color TIRFM study reveals a new form of inflammatory regulation, in which a lipid kinase and ion channel reciprocally regulate each other to amplify the response to painful stimuli.
    1. Neuroscience

    Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery

    Ying Wang, Wei Wu ... Xiao-Ming Xu
    Retrograde transport of NT-3 stimulated the reorganization of lumbar neural circuitry and synaptic connectivity remote to a thoracic SCI, along with improved behavioral recovery.
    1. Cell Biology
    2. Developmental Biology

    Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

    Leah C Biggs, Otto JM Mäkelä ... Marja L Mikkola
    The hair follicle dermal condensate is populated via migration, and the cells exhibit early changes in cell shape and cell cycle status; Fgf20 primes these cellular and molecular events.