5,128 results found
    1. Neuroscience

    Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles

    Julie M Sadino, Xander G Bradeen ... Zoe R Donaldson
    Pair bond induced transcriptional changes in the nucleus accumbens erode after long-term partner separation.
    1. Neuroscience

    Sexual coordination in a whole-brain map of prairie vole pair bonding

    Morgan L Gustison, Rodrigo Muñoz-Castañeda ... Steven M Phelps
    A brain-wide map of neural activation reveals how sexual experience becomes a pair bond in the monogamous prairie vole.
    1. Cancer Biology

    Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus

    Asieh Naderi, Elham Soltanmaohammadi ... Hippokratis Kiaris
    Monogamous rodents of the genus Peromyscus, upon disruption of pair bonds, acquire increased oncogenic activity.
    1. Neuroscience

    Dopamine and opioid systems interact within the nucleus accumbens to maintain monogamous pair bonds

    Shanna L Resendez, Piper C Keyes ... Brandon J Aragona
    The neural mechanisms that underlie the maintenance of social bonds between prairie voles suggest that social support networks may be a powerful way of treating addiction.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Punctuated evolution and transitional hybrid network in an ancestral cell cycle of fungi

    Edgar M Medina, Jonathan J Turner ... Nicolas E Buchler
    Cell cycle network evolution in a fungal ancestor was punctuated by the arrival of a viral DNA-binding protein that was permanently incorporated into the regulatory network controlling cell cycle entry.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level

    Daniel Coutandin, Christian Osterburg ... Volker Dötsch
    p63 uses an intricate network of domain-domain interactions to control its function in long-term quality maintenance of resting oocytes.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other

    Divya Nandakumar, Manjula Pandey, Smita S Patel
    A detailed model of the T7 replisome with the precise positions of the helicase and polymerase at the replication fork explains how catalysis by the two enzymes is coordinated.
    1. Structural Biology and Molecular Biophysics

    Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15

    Luba Mahbub, Guennadi Kozlov ... Kalle Gehring
    ADP-ribosylation factor-like GTPase 15, an atypical small GTPase, binds to cystathionine-β-synthase-pair domain divalent metal cation transport mediator (CNNM) membrane proteins to inhibit divalent cation efflux by CNNM proteins and influx by transient receptor potential ion channel subfamily M member 7.
    1. Neuroscience

    Brain functional networks associated with social bonding in monogamous voles

    M Fernanda López-Gutiérrez, Zeus Gracia-Tabuenca ... Sarael Alcauter
    Brain functional connectivity shows a neurobiological predisposition to social bonding, and network-wide changes occur as a result of cohabitation in the prairie vole.
    1. Cell Biology

    Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami

    Shimaa A Abdellatef, Hisashi Tadakuma ... Keiko Hirose
    A pair of microtubules, ensembles of oppositely oriented axonemal dyneins, and inter-microtubule crosslinkers are the minimum components needed for oscillation and repetitive bending motions.

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