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    1. Neuroscience

    Spatiotemporal interplay between multisensory excitation and recruited inhibition in the lamprey optic tectum

    Andreas A Kardamakis et al.
    Signals conveyed from two different senses from a given point in space converge onto the same neurons of the optic tectum that trigger the gaze-control-system, and at the same time inhibit other parts of the tectal motor map.
    1. Neuroscience

    Reconfiguration of functional brain networks and metabolic cost converge during task performance

    Andreas Hahn et al.
    Cognitive performance is supported by symbiotic metabolic and neuro-vascular responses in task-specific brain networks.
    1. Neuroscience

    Assessing reliability in neuroimaging research through intra-class effect decomposition (ICED)

    Andreas M Brandmaier et al.
    In human neuroimaging, the intra-class effect decomposition (ICED) framework indexes overall reliability, and enables researchers to identify and quantify multi-source contributions to measurement error with the goal of developing more reliable measures.
    1. Plant Biology

    Lipid transfer from plants to arbuscular mycorrhiza fungi

    Andreas Keymer et al.
    Identification of two arbuscular mycorrhiza-specific lipid biosynthesis mutants and fatty acid transfer experiments reveal that host plant lipids are transferred to symbiotic fungi and needed for their development.
    1. Structural Biology and Molecular Biophysics

    Ion Channels: From ions to insulin

    Voula Kanelis
    Electron cryo-microscopy has revealed the three-dimensional structure of a potassium channel that has a central role in regulating the release of insulin from the pancreas.
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    1. Developmental Biology
    2. Human Biology and Medicine

    Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

    Jonghyeob Lee et al.
    Cells from the human pancreatic duct can be grown in culture and triggered to become insulin-producing cells, which could potentially be transplanted into patients with diabetes.
    1. Cell Biology

    Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish

    Sharan Janjuha et al.
    During aging, the pancreatic endocrine islets undergo chronic inflammation, which is associated with a reduced capacity for self-renewal of the insulin-producing beta-cells in zebrafish.
    1. Developmental Biology

    Reconstructing human pancreatic differentiation by mapping specific cell populations during development

    Cyrille Ramond et al.
    A set of cell surface markers reconstruct human pancreatic differentiation and enable the segregation of pancreatic functions into specific populations.
    1. Cancer Biology

    Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice

    Yaqing Zhang et al.
    In the pancreas, reciprocal interactions between epithelial cells and myeloid cells determine the balance between tissue repair and carcinogenesis by regulating acinar cell plasticity through differential activation of EGFR/MAPK signaling.
    1. Cell Biology
    2. Developmental Biology

    A new mode of pancreatic islet innervation revealed by live imaging in zebrafish

    Yu Hsuan Carol Yang et al.
    A novel mode of organ innervation, whereby neurons establish connections with their targets before migrating away, was revealed by live imaging of the developing zebrafish pancreas.