Skip to Content
eLife home page
Submit my research
(via ORCID - An ORCID is a persistent digital identifier for researchers)
Browse the search results
Page 2 of 8
The origins and consequences of
variants in pancreatic adenosquamous carcinoma
Jacob T Polaski et al.
mutations were reportedly present at high frequencies in a cohort of pancreatic adenosquamous carcinoma patients, but these lesions are unlikely to be functional drivers of this cancer subtype.
Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
Alba Nicolas-Boluda et al.
Tumor stiffness blocks T cell migration in tumors.
Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation
Karoliina Stefanius et al.
Exosomes secreted from pancreatic cancer cells can function as a classic initiator in the multi-step cellular transformation process.
Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
Akikazu Harada et al.
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer
Christina R Adams et al.
The GLI2 transcription factor is a master regulator of the aggressive basal-like subtype of pancreatic cancer and enables adaptation to oncogenic KRAS ablation.
Arid1a restrains Kras-dependent changes in acinar cell identity
Geulah Livshits et al.
Arid1a loss in the pancreas enables an irreversible reprogramming of cell fate that is dependent on both cellular and genetic context.
Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice
Shun Kishimoto et al.
Using noise suppression, real-time imaging of glucose metabolism is possible by 13C MRI and reveals previously undetected metabolic differences within tumors.
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
Jonghyeob Lee et al.
Cells from the human pancreatic duct can be grown in culture and triggered to become insulin-producing cells, which could potentially be transplanted into patients with diabetes.
Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
Takahisa Maruno et al.
Genetic lineage tracing approach combined with live imaging visualized the functional stem cell activity of Doublecortin-like kinase 1
cells within pancreatic cancer in vivo.
NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
Zhi-Jie Xiao et al.
NFATc2 maintains the drug-induced TIC phenotypes through trans-activating SOX2/ALDH1A1 expression and scavenging stress from ROS.
Be the first to read new articles from eLife
Sign up for email alerts
Back to top