Cooperativity between two transcription regulators occurs through protein-protein interactions with a general transcription factor complex and potentiates the parallel evolution of their DNA binding sites.

Cis-regulation such as enhancers and promoters plays a major role in parallel gene expression divergence and has features that make it a well-poised substrate for adaptive evolution.

Human telomerase unfolds and extends parallel G-quadruplexes using a unique mechanism involving its RNA template.

Influenza evolution within infected hosts recapitulates many evolutionary dynamics observed at the global scale.

Genetic architecture governs the evolvability of adaptive paths providing a framework for evolutionary forecasting.

Genome sequencing of mice selected for longer limbs reveals that rapid selection response is due to both discrete loci and polygenic adaptation.

A combination of massively parallel reporter assays and mass spectrometry uncovers the regulation of previously unexplored promoters across the Escherichia coli genome.

A proposal for a complete cellular/network implementation of trial-and-error motor learning in the olivo-cerebellar system.

Evolutionary adaptation to a constitutive perturbation of DNA replication reveals that adaptive mutations in three conserved pathways interact to restore faithful chromosome replication and segregation.

Experimental evolution shows that when selection acts on two traits constrained by a trade-off, the direction of phenotypic evolution depends on the environment.