4,065 results found
    1. Neuroscience

    Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

    Kang-Ying Qian et al.
    Male pheromone environment increases the cholinergic synaptic transmission at the neuromuscular junction in Caenorhabditis elegans hermaphrodites during development, decreasing hermaphrodites' locomotion activity and promoting mating efficiency.
    1. Developmental Biology

    Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

    Georges Raad et al.
    Predisposition to obesity-associated diseases is dependent on the ancestors' diet.
    1. Evolutionary Biology

    Striking parallels between dorsoventral patterning in Drosophila and Gryllus reveal a complex evolutionary history behind a model gene regulatory network

    Matthias Pechmann et al.
    Crucial functions of Toll signalling during dorsoventral axis formation might have evolved convergently in flies and crickets.
    1. Neuroscience

    Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex

    Shinya Ohara et al.
    The connection from layer Vb-to-Va neurons, a key component of the canonical hippocampal-cortical output circuit, which is allegedly crucial for memory consolidation, is relatively stronger in lateral entorhinal cortex compared with the medial entorhinal cortex, thus suggesting different operating principles.
    1. Neuroscience

    Slowing the body slows down time perception

    Rose De Kock et al.
    The perception of time is influenced by movement environments, with slower movements associated with shorter perceived time intervals.
    1. Microbiology and Infectious Disease

    Functional insights from a surface antigen mRNA-bound proteome

    Larissa Melo do Nascimento et al.
    A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.
    1. Neuroscience

    A visual pathway for skylight polarization processing in Drosophila

    Ben J Hardcastle et al.
    Circuit tracing and in vivo calcium imaging reveals neurons conveying polarized light information from photoreceptors to the central brain, transforming patterns in the sky into a directional cue for navigation.
    1. Biochemistry and Chemical Biology

    Virus Engineering: ORACLE reveals a bright future to fight bacteria

    Willow Coyote-Maestas, James S Fraser
    A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.
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    1. Computational and Systems Biology

    Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures

    Martin Jinye Zhang et al.
    Comprehensive single-cell transcriptome analysis reveals global and tissue-specific aging markers and characterizes the heterogeneous aging status of different cell types and tissues in mouse.
    1. Neuroscience

    Circuit organization of the excitatory sensorimotor loop through hand/forelimb S1 and M1

    Naoki Yamawaki et al.
    Cell-type-specific circuit analysis reveals a highly polysynaptic pattern of excitatory feedforward connections along the somatosensory-to-motor loop, from cuneate via VPL thalamus to S1 and M1 cortex and corticospinal neurons.

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