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    1. Physics of Living Systems

    Free volume theory explains the unusual behavior of viscosity in a non-confluent tissue during morphogenesis

    Rajsekhar Das, Sumit Sinha ... D Thirumalai
    Theoretical explanation and a novel mechanism are given for the observation that viscosity of embryonic non-confluent tissue shows glass-like behavior till a critical cell density and saturates at higher densities.
    1. Neuroscience

    Recurrent network model for learning goal-directed sequences through reverse replay

    Tatsuya Haga, Tomoki Fukai
    The combination of short-term and long-term plasticity enables hippocampus to learn goal-directed paths through replay in a reversed order.
    1. Neuroscience

    Shallow neural networks trained to detect collisions recover features of visual loom-selective neurons

    Baohua Zhou, Zifan Li ... Damon A Clark
    When artificial networks modeled on a Drosophila neuron are tasked with discriminating objects on collision course from other visual scenes, their optimized solutions reproduce many functional features of the original loom-selective neuron.
    1. Neuroscience

    Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding

    Ching Fang, Jack Lindsey ... Selmaan Chettih
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Beyond gradients: Factorized, geometric control of interference and generalization

    Daniel N Scott, Michael J Frank
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Neuroscience

    Mushroom body evolution demonstrates homology and divergence across Pancrustacea

    Nicholas James Strausfeld, Gabriella Hanna Wolff, Marcel Ethan Sayre
    Demonstrating extreme diversity across crustaceans while contrasting with evolutionary stability in insects, mushroom body homologues further underpin the unity of Pancrustacea and shed new light on arthropod brain evolution.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex

    Colin Echeverría Aitken, Petra Beznosková ... Jon R Lorsch
    Eukaryotic translation initiation factor 3 (eIF3) is required to stabilize the binding of mRNA at the exit channel of the small ribosomal subunit and acts at the entry channel to accelerate mRNA recruitment to the translation preinitiation complex.
    1. Neuroscience

    Spatially targeted inhibitory rhythms differentially affect neuronal integration

    Drew B. Headley, Benjamin Latimer ... Satish S. Nair
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Active dendrites enable robust spiking computations despite timing jitter

    Thomas SJ Burger, Michael E Rule, Timothy O’Leary
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Computational and Systems Biology
    2. Neuroscience

    From single neurons to behavior in the jellyfish Aurelia aurita

    Fabian Pallasdies, Sven Goedeke ... Raoul-Martin Memmesheimer
    A multiscale computational nerve net model describes how the activity of individual neurons controls the swimming motion of a jellyfish in its hydrodynamic environment.