261 results found
    1. Ecology

    A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite

    Meret Huber et al.
    An insect digestive enzyme metabolizes a plant defense compound and thereby modulates herbivore performance and host plant choice, which in turn may alter plant defense evolution in nature.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Common host variation drives malaria parasite fitness in healthy human red cells

    Emily R Ebel et al.
    Human red blood cells from healthy donors display marked biophysical and genetic variation that impacts the growth of Plasmodium falciparum malaria parasites, outside of known disease alleles.
    1. Cell Biology
    2. Genetics and Genomics

    Analysis of meiosis in Pristionchus pacificus reveals plasticity in homolog pairing and synapsis in the nematode lineage

    Regina Rillo-Bohn et al.
    Investigation of meiosis in the nematode Pristionchus pacificus has illuminated evolutionary variation in this essential aspect of reproduction and established a new model for future study.
    1. Evolutionary Biology
    2. Physics of Living Systems

    A framework for studying behavioral evolution by reconstructing ancestral repertoires

    Damián G Hernández et al.
    The behavioral repertoires from six species of flies are measured, and a statistical approach is developed to predict co-evolving behaviors, providing a potential framework for exploring behavioral evolution.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

    Giulia Bandini et al.
    The activity, localization, and essentiality of TbFUT1, together with its ability to complement Leishmania parasites lacking the homologous gene, suggest the presence of an uncommon and conserved mitochondrial fucosylation pathway required for kinetoplastid parasites viability.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade

    Axel A Guzmán-Solís et al.
    The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.
    1. Cell Biology
    2. Developmental Biology

    Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish

    Meredith H Wilson et al.
    Fluorescent perilipin zebrafish lines are powerful new tools for studying lipid droplet dynamics in health and disease.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation

    Hyeogsun Kwon et al.
    Single-cell RNA-seq analysis reveals an increased complexity of mosquito hemocytes, enabling the functional and molecular characterization of immune cell sub-populations in Anopheles gambiae.
    1. Physics of Living Systems

    Effect of malaria parasite shape on its alignment at erythrocyte membrane

    Anil K Dasanna et al.
    A numerical model of malaria parasite adhesion to an erythrocyte shows that the original egg-like shape of merozoites is more robust than other shapes in negotiating various physiological conditions during the alignment process upon erythrocyte invasion.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

    Barbara H Stokes et al.
    Plasmodium falciparum K13 mutations confer resistance to the antimalarial artemisinin in Asian and African parasites, with most gene-edited mutant K13 African parasite lines showing a fitness cost that may predict slow dissemination of artemisinin resistance in high-transmission settings.

Refine your results by:

Type
Research categories