Oxaliplatin-resistant colorectal cancer cells exhibit unregulated death receptor 4 expression with increased receptor palmitoylation and translocation into lipid rafts, increasing their sensitivity to apoptosis via TRAIL.
The extension of covariation analyses to proteins that coevolve but do not physically interact enabled identification of selectivity residues in quorum sensing proteins, providing insight into the evolution of signaling systems.
Items at different positions of a sequence are maintained in distinct latent states of working memory system and are reactivated in reverse order over time, which is further related to recency effect in memory behavior.
Exposure to Bacillus thuringiensis (Bt) selects for beneficial interactions between the target insect pest (Helicoverpa armigera) and its symbiotic densovirus that enhances its performance on Bt-crops under field conditions.
Outer membrane vesicles serve as decoys to reduce the chance of direct polymyxin B (PMB) binding to cells, which partly explains why many clinical isolates and microbial communities can be protected against PMB treatment.