436 results found
    1. Computational and Systems Biology

    Efficient coding in biophysically realistic excitatory-inhibitory spiking networks

    Veronika Koren, Simone Blanco Malerba ... Stefano Panzeri
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation

    James B Isbister, András Ecker ... Michael W Reimann
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    A functional model of adult dentate gyrus neurogenesis

    Olivia Gozel, Wulfram Gerstner
    The GABA input switching from excitatory to inhibitory during maturation of adult-born dentate granule cells is crucial for their integration into the preexisting circuit.
    1. Neuroscience

    Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice

    Evan D Vickers, David A McCormick
    Procedures were developed to perform mesoscale 2-photon Ca2+ imaging simultaneously from all of mouse dorsolateral neocortex, facilitating identification of widespread neural ensembles with activity related to diverse aspects of behavior.
    1. Neuroscience

    Attentional modulation of neuronal variability in circuit models of cortex

    Tatjana Kanashiro, Gabriel Koch Ocker ... Brent Doiron
    Attention reduces noise correlations through enhancing inhibitory feedback in cortical networks.
    1. Neuroscience

    Mechanisms of competitive selection: A canonical neural circuit framework

    Shreesh P Mysore, Ninad B Kothari
    A first principles, neuro-computational framework proposes a path for the experimental dissection of neural circuit mechanisms of competitive selection across brain areas and animal species.
    1. Developmental Biology
    2. Neuroscience

    Identification of neurodevelopmental organization of the cell populations of juvenile Huntington’s disease using dorso-ventral HD organoids and HD mouse embryos

    Karolina Świtońska-Kurkowska, Jakub Kubiś ... Maciej Figiel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Synaptic connectivity to L2/3 of primary visual cortex measured by two-photon optogenetic stimulation

    Travis A Hage, Alice Bosma-Moody ... Gabe J Murphy
    A combination of multicellular recording and optogenetic photostimulation was used to deeply characterize the spatial profiles and effective strengths of intralaminar and translaminar synaptic connections from genetically defined neuronal populations in the visual cortex of adult mouse.
    1. Neuroscience
    2. Physics of Living Systems

    Beta oscillations and waves in motor cortex can be accounted for by the interplay of spatially structured connectivity and fluctuating inputs

    Ling Kang, Jonas Ranft, Vincent Hakim
    The observed activity of the motor cortex in space and time is reproduced by a model with a specific structure of the inputs to the motor cortex.
    1. Neuroscience

    Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention

    Amélie Aussel, Ian C Fiebelkorn ... Benjamin Rafael Pittman-Polletta
    A biophysical cortical circuit model reveals how thalamic inputs mediate complex dynamics in the frontal eye fields and lateral intraparietal area, enabling rhythmic enhancements in visual sensitivity observed behaviorally.

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