Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.

The gene-regulatory enhancers h56D and S5E2 restrict transgene expression to GABAergic and parvalbumin-positive interneurons, respectively, across marmoset cortical layers, thus representing a promising tool for circuit dissection in non-human primates.

A brain-wide mapping of the direct inputs to striatal cholinergic and parvalbumin interneurons reveals connectivity differences and implies their distinct roles in regulating striatal function.

In rodents and primates, there are two subtypes of parvalbumin-expressing interneurons that provide novel substrates for selective inhibition in the striatum.

Electrophysiological and behavioural experiments reveal that parvalbumin interneuron-mediated increases in neocortical-hippocampal interactions are necessary for successful memory consolidation.

Parvalbumin-containing inhibitory neurons are crucial for expression of plasticity in adult visual cortex that supports visual recognition memory, but not for expression of ocular dominance plasticity that results from monocular deprivation.

Parvalbumin positive GABAergic neurons in the ventral zona incerta receive input from somatosensory cortex and enhance sound-induced flight behavior, which underlies a cross-modality facilitation of defensive behavior by somatosensory input.

An excess of novel non-canonical subtypes of parvalbumin+ interneurons in a mouse model of classical lissencephaly, which possess non-fast-spiking physiological properties, may contribute to network hyperexcitability common in this model.

New methods for investigating connectivity between genetically defined neuronal populations are introduced and used to investigate the organisation of excitatory-inhibitory interactions in the superficial entorhinal cortex.

Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.