A study that models the evolution of drug resistance in tumors reveals that drugs are more effective when given in combination than sequentially, and that cure is much more likely when the drugs target different pathways.

Genomic evidence suggests that L-gulonolactone oxidase-the terminal enzyme in vitamin C synthesis, which has been repeatedly lost throughout animal evolution-was lost in plants and other photosynthetic eukaryotes following plastid acquisition.

NCOA4, the ferritin autophagy receptor, is regulated by HERC2 in an iron-dependent manner and is critical for red blood cell development.

Finch embryos are laid at an earlier stage than other avian embryos and contain cells with similar properties to pluripotent embryonic stem cells from mice.

In situ measurements of muscular twitch speed reveal one of the fastest vertebrate limb muscles on record, which evolved in association with extravagant courtship displays that include rapid limb movements.

A new mitochondrial protein degradation pathway selectively sorts and destroys a subset of the mitochondrial membrane proteome to protect mitochondria in times of stress.

Two therapsid clades, dicynodonts and cynodonts, independently acquired and developed an endotherm-like thermoregulation during the Late Permian period, that probably helped them to survive the major global climate and environmental fluctuations of the end-Permian.

Testing of fitness-related benefits in migratory population of European blackbirds offers confirming predictions of theoretical models on the evolution and maintenance of migration.

Basal ganglia gene coexpression patterns shift across the sensorimotor critical period for vocal learning.

We are starting to understand how the cerebellum contributes to vocal learning in songbirds.