Jonathan Rodriguez, Abdon Iniguez ... Richard A Van Etten
A physiological mathematical model of chronic myeloid leukemia, validated by experiments in transgenic mice and clinical data, identifies mechanisms underlying the response to tyrosine kinase inhibitor therapy, predicts biomarkers of primary resistance, and suggests new strategies to improve treatment outcomes.
Chad M Eliason, Jenna M McCullough ... Michael J Andersen
Treating color patterns in a geometric morphometrics framework reveals rapid rates of color evolution that are explained by a combination of intrinsic organismal features (color variation among patches) and geography within a cosmopolitan radiation of birds.
Ryan W Schwark, Matthew J Fuxjager, Marc F Schmidt
The midbrain periaqueductal grey is a conserved mediator of elaborate courtship behavior in a range of vertebrate taxa, likely shaping how this behavior diversifies across the tree of life.
Marie C Russell, Catherine M Herzog ... Andrew C McCall
While predators can clearly reduce mosquito populations by consumption, they can also have non-consumptive effects on mosquito body size and oviposition behavior, and these effects on vector traits can influence infectious disease dynamics.
Mark E Hauber, Matthew IM Louder, Simon C Griffith
The genetic and behavioral diversity of the zebra finch, both in the wild and in captivity, make it well-suited for neuroethological studies of vocal learning, culture, and social bonding.
FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
Scott McWilliams, Barbara Pierce ... Ulf Bauchinger
Migratory birds with fuel stores composed of more omega-6 fats saved energy during long-duration flights, but this short-term energy saving came at the long-term cost of higher oxidative damage.
Catherine G Triandafillou, Christopher D Katanski ... D Allan Drummond
When translation stops, cells require intracellular acidification to turn on the conserved heat shock response during stress, and stress-triggered acidification (common in eukaryotes) is adaptive, promoting cell and population fitness.
Four species of seabird produce efficient propulsive wakes while flying in the air and while swimming underwater suggesting that selection has optimized these species for locomotion in remarkably different fluids.