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    1. Developmental Biology
    2. Evolutionary Biology

    Characterization of the finch embryo supports evolutionary conservation of the naive stage of development in amniotes

    Siu-Shan Mak, Cantas Alev ... Raj K Ladher
    Finch embryos are laid at an earlier stage than other avian embryos and contain cells with similar properties to pluripotent embryonic stem cells from mice.
    1. Neuroscience

    Accelerated redevelopment of vocal skills is preceded by lasting reorganization of the song motor circuitry

    Michiel Vellema, Mariana Diales Rocha ... Manfred Gahr
    The ability to quickly re-acquire a previously lost motor skill is associated with lasting synaptic changes in the brain circuit that controls that motor skill.
    1. Neuroscience

    Lesions in a songbird vocal circuit increase variability in song syntax

    Avani Koparkar, Timothy L Warren ... Lena Veit
    A forebrain nucleus contributes specifically to the variability of syllable sequencing in songs of Bengalese finches, a songbird with complex syntactic song structure.
    1. Neuroscience

    Male cuticular pheromones stimulate removal of the mating plug and promote re-mating through pC1 neurons in Drosophila females

    Minsik Yun, Do-Hyoung Kim ... Young-Joon Kim
    Identification of central neural circuits and sensory pathways underlying social-sexual modulation of sperm ejection in female Drosophila unraveled cryptic mate choice, a mechanism of post-copulatory sexual selection.
    1. Evolutionary Biology
    2. Plant Biology

    Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes

    Glen Wheeler, Takahiro Ishikawa ... Nicholas Smirnoff
    Genomic evidence suggests that L-gulonolactone oxidase-the terminal enzyme in vitamin C synthesis, which has been repeatedly lost throughout animal evolution-was lost in plants and other photosynthetic eukaryotes following plastid acquisition.
    1. Evolutionary Biology
    2. Cancer Biology

    Evolutionary dynamics of cancer in response to targeted combination therapy

    Ivana Bozic, Johannes G Reiter ... Martin A Nowak
    A study that models the evolution of drug resistance in tumors reveals that drugs are more effective when given in combination than sequentially, and that cure is much more likely when the drugs target different pathways.
    1. Ecology
    2. Epidemiology and Global Health

    Mosquito community composition shapes virus prevalence patterns along anthropogenic disturbance gradients

    Kyra Hermanns, Marco Marklewitz ... Sandra Junglen
    Analysis of naturally infected mosquitoes shows that ecosystem disturbance can lead to a turnover in host community composition and that more individuals of a single species are a key driver of virus emergence.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Correlated evolution between repertoire size and song plasticity predicts that sexual selection on song promotes open-ended learning

    Cristina M Robinson, Kate T Snyder, Nicole Creanza
    A longer birdsong-learning window evolves in response to sexual selection for song complexity and is associated with faster evolution of song performance characteristics.
    1. Cell Biology

    Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

    Joseph D Mancias, Laura Pontano Vaites ... J Wade Harper
    NCOA4, the ferritin autophagy receptor, is regulated by HERC2 in an iron-dependent manner and is critical for red blood cell development.
    1. Cell Biology

    Selective sorting and destruction of mitochondrial membrane proteins in aged yeast

    Adam L Hughes, Casey E Hughes ... Daniel E Gottschling
    A new mitochondrial protein degradation pathway selectively sorts and destroys a subset of the mitochondrial membrane proteome to protect mitochondria in times of stress.