563 results found
    1. Neuroscience

    Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection

    Ilya A Rybak, Natalia A Shevtsova ... Alain Frigon
    Computational modeling based on experimental data reveals how spinal sensorimotor circuits control cycle and phase durations during treadmill locomotion after an incomplete spinal cord injury.
    1. Neuroscience

    Glia control experience-dependent plasticity in an olfactory critical period

    Hans C Leier, Alexander J Foden ... Heather T Broihier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors

    Vincent Huson, Wade G Regehr
    Different glutamate receptors have specialized roles that allow cerebellar unipolar brush cells to transform realistic mossy fiber input patterns into a continuum of temporal responses.
    1. Neuroscience

    Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing

    Robert A Bruce, Matthew Weber ... Kumar Narayanan
    Dorsomedial D2-MSNs and D1-MSNs exhibit opposing dynamics during interval timing, however disrupting either MSN type produces similar effects on behavior, highlighting the complementary roles of striatal pathways in cognitive operations.
    1. Cell Biology

    Binding of LncDACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility

    Genlong Xue, Jiming Yang ... Zhenwei Pan
    lncDACH1 is a novel regulator of sodium channel, which suppresses the membrane trafficking of Nav1.5 by disturbing the function of dystrophin.
    1. Neuroscience

    Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

    Christopher Bell, Lukas Kilo ... Stefanie Ryglewski
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Synaptic input architecture of visual cortical neurons revealed by large-scale synapse imaging without backpropagating action potentials

    Satoru Kondo, Kohei Kikuta, Kenichi Ohki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Bridging the gap between presynaptic hair cell function and neural sound encoding

    Lina María Jaime Tobón, Tobias Moser
    Synaptic diversity in the ear's inner hair cells significantly empowers sound encoding to enable our processing of sounds across a broad range of intensities.
    1. Neuroscience

    The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks

    Han Lu, Sandra Diaz ... Andreas Vlachos
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances

    Jian Qiu, Margaritis Voliotis ... Martin J Kelly
    Kiss1ARH neurons transition from synchronous to burst firing under preovulatory levels of E2, causing a shift from peptidergic to glutamatergic transmission that drives the GnRH surge through enhanced glutamate neurotransmission.
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