Browse the search results

Page 2 of 543
    1. Plant Biology

    Dormancy-specific imprinting underlies maternal inheritance of seed dormancy in Arabidopsis thaliana

    Urszula Piskurewicz et al.
    A genomic imprinting program in the endosperm of Arabidopsis mature seeds is dynamically adjusted according to seed dormancy levels and regulates germination.
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    RNA-Binding Proteins: A matter of balance

    Aaron D Gitler, John D Fryer
    New analyses shift the view that some forms of amyotrophic lateral sclerosis and frontotemporal dementia are due to defects in a single RNA-binding protein.
    Insight
    Available as:
    • HTML
    • PDF
    1. Genetics and Genomics

    Genetic variation in offspring indirectly influences the quality of maternal behaviour in mice

    David George Ashbrook et al.
    A cross-fostered population of mice reveals loci on offspring chromosomes 5 and 7 that modify the behaviour of their mothers, along with evidence of coadaptation between offspring and parental traits.
    1. Biochemistry and Chemical Biology

    Kinetics of initiating polypeptide elongation in an IRES-dependent system

    Haibo Zhang et al.
    The retarding effect of a ribosome-bound internal ribosome entry site on eukaryotic protein synthesis is largely overcome following translocation of tripeptidyl-tRNA.
    1. Developmental Biology

    Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning

    Jose L Pelliccia et al.
    Genetic analyses demonstrate that Gdf3/Vg1 is a maternal effect gene required for robust Nodal signaling during different phases of embryogenesis including germ-layer formation, Kupffer's vesicle morphogenesis, and left-right patterning.
    1. Neuroscience

    Internal models for interpreting neural population activity during sensorimotor control

    Matthew D Golub et al.
    A novel analysis of neural activity recorded in monkeys performing a “brain-machine interface” task reveals that a mismatch between motor effectors and the brains’ internal models of those effectors can explain a substantial portion of movement errors.
    1. Developmental Biology
    2. Plant Biology

    Paternally expressed imprinted genes establish postzygotic hybridization barriers in Arabidopsis thaliana

    Philip Wolff et al.
    Hybridization barriers in Arabidopsis thaliana can be established by paternally expressed imprinted genes (PEGs) that affect cellularization of the endosperm during seed development.
    1. Developmental Biology

    Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

    Sobhika Agarwala et al.
    The cell junction-associated protein Amotl2a controls tissue size in the zebrafish lateral line primordium by limiting the activity of the Hippo effector Yap1 and the Wnt effector Lef1.
    1. Neuroscience

    Activation of the same mGluR5 receptors in the amygdala causes divergent effects on specific versus indiscriminate fear

    Mohammed Mostafizur Rahman et al.
    Activation of the same glutamate receptor in the lateral amygdala gives rise to distinct effects on specific versus indiscriminate fear by modulating intrinsic excitability and synaptic plasticity.
    1. Neuroscience

    Distinct lateral inhibitory circuits drive parallel processing of sensory information in the mammalian olfactory bulb

    Matthew A Geramita et al.
    Distinct lateral inhibitory circuits affect spiking in olfactory bulb mitral and tufted cells differently, which ultimately allows each cell type to best discriminate between similar odors in separate concentration ranges.