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    1. Developmental Biology

    Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

    Georges Raad, Fabrizio Serra ... Valerie Grandjean
    Predisposition to obesity-associated diseases is dependent on the ancestors' diet.
    1. Ecology
    2. Evolutionary Biology

    Mandrill mothers associate with infants who look like their own offspring using phenotype matching

    Marie JE Charpentier, Clémence Poirotte ... Julien P Renoult
    Mandrill mothers know best because they use their offspring’s facial resemblance with other infants to guide their social opportunities towards similar-looking ones as an adaptive maternal behavior.
    1. Developmental Biology

    Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally

    Jadiel A Wasson, Ashley K Simon ... David J Katz
    Epigenetic reprogramming by LSD1/KDM1A acts at fertilization in mice to enable embryogenesis and prevent behavioural abnormalities.
    1. Plant Biology

    Dormancy-specific imprinting underlies maternal inheritance of seed dormancy in Arabidopsis thaliana

    Urszula Piskurewicz, Mayumi Iwasaki ... Luis Lopez-Molina
    A genomic imprinting program in the endosperm of Arabidopsis mature seeds is dynamically adjusted according to seed dormancy levels and regulates germination.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    The Wolbachia cytoplasmic incompatibility enzyme CidB targets nuclear import and protamine-histone exchange factors

    John Frederick Beckmann, Gagan Deep Sharma ... Mark Hochstrasser
    Genetic and proteomic screening with Wolbachia's CidB enzyme reveal the mechanisms and targets of cytoplasmic incompatibility (CI).
    1. Chromosomes and Gene Expression

    Intergenerational epigenetic inheritance of cancer susceptibility in mammals

    Bluma J Lesch, Zuzana Tothova ... David C Page
    Genetic knockout of the histone demethylase Kdm6a in the mouse germ line leads to elevated cancer incidence in genetically wild type offspring.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Parent-of-origin effects propagate through networks to shape metabolic traits

    Juan F Macias-Velasco, Celine L St Pierre ... Heather A Lawson
    Non-imprinted genes can contribute to parent-of-origin effects on phenotype through interactions with imprinted genes.
    1. Developmental Biology
    2. Genetics and Genomics

    Constraint and divergence of global gene expression in the mammalian embryo

    Noah Spies, Cheryl L Smith ... Arend Sidow
    Embryonic gene expression is strongly influenced by maternal genetic variation and by embryonic variation that acts in cis but not in trans.
    1. Cell Biology

    Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation

    Kenji Sugioka, Danielle R Hamill ... Bruce Bowerman
    A genetic screen and live cell imaging show that a newly identified coiled-coil protein called SAS-7 is the earliest acting factor in centriole assembly yet identified in the roundworm Caenorhabditis elegans.
    1. Chromosomes and Gene Expression

    Combinations of maternal-specific repressive epigenetic marks in the endosperm control seed dormancy

    Hikaru Sato, Juan Santos-González, Claudia Köhler
    Analyses of cell type-specific data show that the maternal alleles of genes related to establishing and breaking seed dormancy are suppressed by different combinations of epigenetic marks in the endosperm of Arabidopsis.