Nathan M Shugarts Devanapally, Aishwarya Sathya ... Antony M Jose
Transport of double-stranded RNA from parental circulation to progeny using the transmembrane protein SID-1 can occur through multiple routes during C. elegans development and buffer heritable changes in gene expression.
The mouse gene Ythdc2 exemplifies an evolutionarily ancient family of crucial regulators of the transition from germline stem cell divisions to meiosis.
Germline mutation rates in mice are shaped by two mutator alleles that interact epistatically, showing that DNA repair defects that map to different loci can have snowballing effects.
Bayly S Wheeler, Erika Anderson ... Barbara J Meyer
A chromosome-wide mechanism balances X-linked gene expression between the sexes in C. elegans, but no similar chromosome-wide mechanism balances gene expression between X chromosomes and autosomes.
Thomas M Houslay, Ryan L Earley ... Alastair Wilson
Behavioural and physiological stress response components are integrated on the major axis of genetic covariation, with implications for health and the understanding of the evolutionary response to stressors.
A comparison between artificially created allopolyploids and natural ones reveals that the latter underwent significant evolutionary steps after their formation.
Beatriz Navarro-Dominguez, Ching-Ho Chang ... Amanda M Larracuente
African haplotypes of a meiotic drive supergene in Drosophila melanogaster called Segregation Distorter show signs of a recent selective sweep, reduced recombination, and increased genetic load.
Mathieu Hénault, Souhir Marsit ... Christian R Landry
Transposable elements are not reactivated in natural hybrids of the yeast Saccharomyces paradoxus, but their accumulation is genotype-specific and is not predicted by the evolutionary divergence between a hybrid's parents.