Browse the search results

Jumping of transposable elements provides DNA-binding sites for the MADS-box transcription factor PHERES1, allowing the regulation of imprinted genes and other key endosperm development genes.

A paternal bias in germline mutation is seen throughout amniotes and may be explained by sex differences in DNA damage and repair after primordial germ cell specification.

Hypoplastic left heart syndrome is reflected by reduced proliferative capacity of patient iPSC-derived cardiomyocytes and requires the activity of LRP2/APOB proteins, likely in conjunction with SHH and WNT signaling pathways.

The PVN-mPFC OT circuit is an important target for the treatment of disorders related to early adverse experiences.

A genomic imprinting program in the endosperm of Arabidopsis mature seeds is dynamically adjusted according to seed dormancy levels and regulates germination.

Zebrafish early embryos initially package their developmental genes and enhancers in 'active' chromatin that subsequently receives polycomb repressive complex 1 (PRC1)-mediated histone H2A ubiquitylation, which confers silencing/poising – prior to Aebp2-PRC2-guided H3K27me3 addition.

By spending more time around infants which physically resemble their own, mandrill mothers may increase how frequently their offspring interact with their paternal half siblings.

Continuous space models indicate that current homing suppression drives may have difficulty eliminating wild mosquito populations, but building a successful drive may still be possible with current tools.

Non-imprinted genes can contribute to parent-of-origin effects on phenotype through interactions with imprinted genes.

Reactivation of paternal Ube3a by an ASO therapy in juvenile and adult mouse models of Angelman syndrome reverses the impairments of EEG power spectrum and sleep pattern, suggesting that these two core disease features may be improved by such therapies.