1,779 results found
    1. Evolutionary Biology
    Paleontology

    Paleontology: A Collection of Articles

    Curated by Ian Baldwin et al.
    eLife has published papers on topics as diverse as paleoproteomics, ancient insects and the discovery of a new hominin species.
  1. September 2014

    Episode 14: September 2014

    In this episode we hear about the spread of the ebola virus, the financial costs of research misconduct, aging in yeast, grooming in flies, and symbiosis between bacteria and fungal cells.
  2. November 2016

    Episode 33: November 2016

    In this episode we hear about the first heartbeat, African sleeping sickness, elephant genetics, the rubber hand illusion and women in science.
  3. May 2014

    Episode 12: May 2014

    In this episode we hear about the neuroscience of chewing, skin cancer, African sleeping sickness, an ancient protein complex, and our editor-in-chief shares his thoughts on scientific publishing.
  4. February 2017

    Episode 36: February 2017

    In this episode we hear about epilepsy, the sushi-belt model of transport in neurons, a mother in ancient Troy, the Amazon rainforest and bias in scientific reporting.
    1. Cell Biology
    2. Neuroscience

    Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans

    Shaarika Sarasija et al.
    In C. elegans, presenilin functions, independent of its gamma-secretase proteolytic activity, to regulate mitochondrial metabolism by controlling ER-mitochondrial calcium transfer and, even in the absence of Abeta signaling, loss of this activity leads to neurodegeneration.
    1. Human Biology and Medicine
    2. Neuroscience

    Down regulation of vestibular balance stabilizing mechanisms to enable transition between motor states

    Romain Tisserand et al.
    Down regulation of the gain from the vestibular sensory sources prior to the initiation of movement is a motor control solution to overcome the reflex-stabilizing mechanisms to enable motion from a postural orientation.
    1. Cell Biology
    2. Neuroscience

    Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

    Qi Wang et al.
    Characterization of Tnc as a selective integrin ligand at the Drosophila NMJ allows for unprecedented insights into our understanding of extracellular matrix/integrin interactions at synaptic locations and reveals novel, distinct presynaptic and postsynaptic integrin functions.
    1. Neuroscience

    Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans

    Xi Chen et al.
    Plexin controls the spatial distribution of synapses by locally inhibiting Rap2 small GTPase activity along the axon, and a Rap2 effector, TNIK, which also plays a key role in inhibiting synapse number.
    1. Cell Biology
    2. Genetics and Genomics

    Rapid re-identification of human samples using portable DNA sequencing

    Sophie Zaaijer et al.
    DNA fingerprinting by portable nanopore sequencing is a novel re-identification method with applications in (clinical) laboratories and biobanks.

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