A new peptidoglycan hydrolase mined from Acinetobacter baumannii proteome by lysin-derived antimicrobial peptide-primed screening strategy undergoes a unique switch between dimer and monomer after heat treatment and protects mice from A. baumannii infection.

Robust NMR approach allowed simultaneous detection of substrate cleavage site and real-time kinetics of hydrolysis for Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM, and revealed D-alanyl-glycine activity for LytM.

Chi3l1 binds to bacterial peptidoglycan, helping anchor and organize bacteria within the mucus layer.

Identifying gain-of-function division variants that suppress the elongated cell division defect phenotype caused by Aeg1 depletion.

The Braun lipoprotein is tethered to peptidoglycan independently from the insertion of newly-synthesized peptidoglycan subunits into the expanding cell wall generating a dynamic equilibrium between free and bound protein forms.

A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall and thus transmits proton motive force from the inner membrane to cell surface.