Cell wall biosynthesis in mycobacteria is regulated by an unusual post-translational regulatory system that contributes to antibiotic tolerance during stress.
Sebastian Pöhl, Manuel Osorio-Valeriano ... Martin Thanbichler
Analyses of the stalked budding bacterium Hyphomonas neptunium and its spiral-shaped relative Rhodospirillum rubrum reveal a conserved morphogenetic module that controls the establishment of complex bacterial cell shapes.
A basidiomycete yeast closely related to fungal smuts is an antagonistic microbe in the Arabidopsis leaf phyllosphere that inhibits infection by Albugo laibachii via a GH25 hydrolase with lysozyme activity.
Allison Hillary Williams, Richard Wheeler ... Ivo Gomperts Boneca
Lytic transglycosylase enhances the activity of its protein partner, and its catalytic domain can be targeted to disrupt cell-wall integrity, protein partner function, and bacterial survival (Neisseria meningitidis) in hosts.
Sophie R Sichel, Benjamin P Bratton, Nina R Salama
The helical cell shape of Helicobacter pylori depends on the polymerizing cytoskeletal protein CcmA’s recruitment to the cell envelope by Csd5 and CcmA’s indirect stabilization of a periplasmic cell wall hydrolase via interactions with the transmembrane protein Csd7.
Distinct surfaces of an interbacterial competition cell wall toxin mediate interactions with different cellular binding partners, resulting in an inherent evolutionary trade-off across the toxin superfamily.
Balanced peptidoglycan synthesis requires regulators, including sigma-I and WalKR, that coordinate the diffusive action of class A PBPs and the directional motion of the MreB-directed elongasome.
