9 results found
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Method development and characterisation of the low-molecular-weight peptidome of human wound fluids

    Mariena JA van der Plas et al.
    Peptidomics method development and analysis of qualitative differences of peptide patterns in human wound fluids provide potential biomarkers for wound healing and infection.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    An open-source computational and data resource to analyze digital maps of immunopeptidomes

    Etienne Caron et al.
    A community-based international effort generates standardized HLA allele-specific peptide assay libraries and enables the analysis of the human immunopeptidome by SWATH mass spectrometry.
    1. Genetics and Genomics
    2. Neuroscience

    Neuropeptide ACP facilitates lipid oxidation and utilization during long-term flight in locusts

    Li Hou et al.
    CRISPR/Cas 9 technology and multiple-omics study reveal an essential regulatory role of neuropeptide ACP in lipid utilization related to prolonged flight of locusts.
    1. Structural Biology and Molecular Biophysics

    Semen amyloids participate in spermatozoa selection and clearance

    Nadia R Roan et al.
    Ex vivo characterization of the interaction of human sperm with semen factors reveals that semen amyloids, previously discovered due to their ability to enhance HIV infection, serve a physiological function by promoting disposal of the defective sperm.
    1. Immunology and Inflammation

    TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

    F Tudor Ilca et al.
    Immunopeptidomics in combination with novel cell-based assays that assess peptide exchange reveal a critical role for the K22-D35 loop of TAPBPR in mediating peptide dissociation and peptide selection on MHC I.
    1. Developmental Biology
    2. Neuroscience
    Pond snail illustration

    The Natural History of Model Organisms: The unlimited potential of the great pond snail, Lymnaea stagnalis

    István Fodor et al.
    The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq

    Julie L Aspden et al.
    Thousands of small Open Reading Frames are translated, and form two distinct classes based on their translational efficiency and bioinformatic indicators.
    1. Evolutionary Biology
    2. Neuroscience

    Tachykinin signaling inhibits task-specific behavioral responsiveness in honeybee workers

    Bin Han et al.
    Neuropeptide tachykinin signaling acts as master regulator of behavioral specialization in honeybees by differentially modulating worker responsiveness to task-specific stimuli.
    1. Immunology and Inflammation

    Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity

    Brogan Yarzabek et al.
    Lymphocytes and monocytes maintain their cell surface HLA-B via different mechanisms, which in turn differently influence cell-surface expression, half-life and peptide receptivity of HLA-B allotypes.

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