Pauline Luczynski, Monica Tramullas ... John F Cryan
Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.
Vijay K Samineni, Jose G Grajales-Reyes ... Robert W Gereau
Circuit and transcriptional analysis shows that genetically defined central amygdala neurons and their projections to the ventral periaqueductal gray mediate behavioral and affective responses to pruritus.
Ryan W Schwark, Matthew J Fuxjager, Marc F Schmidt
The midbrain periaqueductal grey is a conserved mediator of elaborate courtship behavior in a range of vertebrate taxa, likely shaping how this behavior diversifies across the tree of life.
Inhibitory neurons in the hypothalamus and amygdala push and pull on the midbrain vocal gating circuit to trigger and suppress ultrasonic vocalization (USV) production in the mouse.
Robert AR Drake, Kenneth A Steel ... Anthony E Pickering
Alterations to brain network communication leading to a progressive loss in descending inhibitory modulation of the spinal cord is a key determinate of pain state development following peripheral nerve injury.
Miguel Antonio Xavier de Lima, Marcus Vinicius C Baldo ... Newton Sabino Canteras
The anterior cingulate cortex provides predictive relationships between the context and the predator threat and influences the acquisition and expression of fear memory to predatory threat.
Alexandra Tinnermann, Christian Sprenger, Christian Büchel
Corticospinal functional MRI reveals that the opioid remifentanil and the level of perceived analgesia modulate coupling strength between the prefrontal cortex, brainstem, and spinal cord.
Integrated imaging analysis of a large multi-center dataset showed that treatment of refractory aggressive behavior with hypothalamic deep brain stimulation is highly effective with specific clinical and neuroimaging features associated with treatment success.
