A previously unappreciated histone methylation pathway helps limit DNA double-strand break formation and recombination in heterochromatin during meiosis.

The nuclear periphery houses compositionally and functionally distinct domains, one of which provides a 'safe zone' for replication and reassembly of heterochromatic genome regions.

Suv39h1 chromodomain possesses nucleic acid-binding activity and this activity is coupled with its H3K9 methylation recognition in assembling heterochromatin.

SUV39H1 histone methyltransferase directly binds chromosome associated RNA to promote constitutive heterochromatin formation.

De novo formation of centromeres creates diverse karyotypes in flies and is accompanied by rapid turnover of centromere-associated satellite repeats.

An RNA-mediated mechanism that stabilizes association of the Suv39h enzymes at mouse heterochromatin is defined.

Ploidy is stably maintained in Saccharomyces cerevisae by a tight coordination between histone levels and cell cycle events.

Fine mapping of transposable element presence/absence variation amongst 216 Arabidopsis strains uncovers widespread novel genetic diversity that underlies differences in transcription and DNA methylation patterns.

The chromosome architectural protein, CTCF, is phosphorylated at Ser²²⁴ in a cell-cycle-dependent manner and abrogation of phosphorylation leads to a cell growth defect.

A lysine-to-methionine mutation in histone H3 dominantly blocks histone H3K9 methylation by trapping its methyltransferase.