15 results found
    1. Computational and Systems Biology
    2. Developmental Biology

    Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18

    Huan Liu et al.
    Analysis of zebrafish periderm enhancers illuminates the conserved DNA of epithelial enhancers across species and prioritizes orofacial-cleft-associated regulatory variants near KRT18/KRT8.
    1. Cell Biology
    2. Developmental Biology

    Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish

    Prateek Arora et al.
    Polarity cascade initiated by aPKC in the periderm is transduced by adherens junction component E-cadherin to the basal epidermis during the development of zebrafish bilayered epidermis.
    1. Cancer Biology
    2. Developmental Biology

    Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

    Julia Hatzold et al.
    A Na,K-ATPase beta subunit can suppress basal cell carcinogenesis either via its osmoregulatory function to avoid hypotonic stress, or by promoting epithelial polarity and adhesiveness of basal keratinocytes from the overlying outer layer.
    1. Cell Biology
    2. Genetics and Genomics

    Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX

    Jiajia Ma et al.
    The serine protease Matriptase orchestrates simultaneous epithelial cell motility and inflammation in pathological states through respective activation of the MAPK pathway and generation of hydrogen peroxide.
    1. Cell Biology
    2. Developmental Biology

    Keratins and plakin family cytolinker proteins control the length of epithelial microridge protrusions

    Yasuko Inaba et al.
    Although intermediate filaments are not widely known to contribute to the morphogenesis of cellular protusions, keratin filaments and cytolinkers are critical for the development of microridge protrusions in zebrafish skin.
    1. Cell Biology

    Science Forum: Vision, challenges and opportunities for a Plant Cell Atlas

    Plant Cell Atlas Consortium et al.
    A Plant Cell Atlas that shows the location and organization of molecules at cellular and tissue levels could have far-reaching consequences for plant sciences.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin

    Damian E Dalle Nogare et al.
    Epithelial cells utilize a covering sheath of motile cells to migrate in confinement.
    1. Neuroscience

    A multicellular rosette-mediated collective dendrite extension

    Li Fan et al.
    Migrating skin carries the amphid rosette vertex anteriorly to extrude and position dendrites.
    1. Neuroscience

    Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington’s nucleus CRH neurons

    Hiroki Ito et al.
    Ponto-spinal CRH neurons in Barrington’s nucleus are a core component of an inferential circuit that regulates autonomous micturition and generates voids when the bladder is full.

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