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Immunology and Inflammation
Microbiology and Infectious Disease
Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome
Isabelle J Marié et al.
Overlapping action of type I, II, and III interferons maintains microbiome homeostasis, prevents IL-17-driven myeloproliferative disease, and protects against inflammatory bowel disease.
Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Zhonghao Deng et al.
Def6 functions as a novel immunoregulator in bone cells via endogenous type-I interferon response to regulate bone remodeling.
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