High PI3K-Akt-mTORC1 activity inhibits Schwann cell differentiation, while after onset of myelination, residual PI3K-Akt-mTORC1 activity promotes myelin growth.

A zebrafish model of neuroblastoma reveals that the tumor suppressor NF1 uses different mechanisms to suppress malignant transformation and to down-modulate normal neural crest cell growth during embryogenesis.

Molecular analysis paints a detailed picture of the distinctiveness and complexities of peripheral somatosensory neurons.

A protein called Megf8 regulates the activity of key signaling molecules involved in the development of the peripheral nervous system.

A novel BAC transgenic mouse model reveals glial restriction of P2X7 expression in the central and peripheral nervous systems.

In the peripheral nervous system, the large GTPase dynamin 2 is required for Schwann cell survival, developmental radial sorting of axons, myelination, and myelin maintenance.

The sensory nerves that carry sensations from the taste buds to the brain induce the formation of the taste buds in the embryo.