Experimental mapping of the joint sequence space of an ancient transcription factor (TF) and its DNA binding sites reveals that epistasis across the molecular interface permitted the evolution of a new and specific TF-DNA complex.

Changes to cellular protein homeostasis reveal widespread advantageous effects of destabilizing mutations, opening the possibility to switch mutational landscapes back-and-forth from permissive to restrictive.

A survey of journals and editors in five areas of research - ecology, economics, medicine, physics and psychology - reveals a range of differences in their approach to peer review.

Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.

Ideas about causality from philosophy can help scientists to better understand how cancerous tumors grow and spread in the body.

The availability of almost all articles from toll access journals in the Sci-Hub repository will disrupt scholarly publishing towards more open models.

The integrated stress response is able to rapidly shut down the synthesis of proteins in eukaryotic cells.

Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.

Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

The COVID-19 pandemic has clearly demonstrated the need for a global system to monitor the dynamics of susceptibility and immunity, as well as infection, during epidemics and pandemics.