A sexually dimorphic circuit node controls a persistent, internal state that promotes fighting and mating in Drosophila, revealing parallels with mammalian systems suggestive of a conserved circuit "motif" controlling social behaviors.
Temporal associative learning enhances persistent firing in lateral entorhinal cortex (LEC) layer III neurons, while aging decreases persistent firing, leading to cognitive impairments.
Simultaneous recordings of neural ensembles in both the frontal and parietal cortices reveal how persistent activity can be maintained in the primate brain during visuospatial working memory.
The auditory cortex temporarily stores task-relevant information by persistently changed neuronal activity of single neurons and of neuronal populations.
Building on previous work (Huang et al., 2016), we show that translational control by p-eIF2α is a defense mechanism that prevents persistent cocaine-induced synaptic synaptic potentiation underlying compulsive drug seeking.
A set of sexually dimorphic neurons in female flies is part of a recurrent neural network and drives minutes-long persistent neural activity and persistent social behaviors.
Combination of in vitro and in vivo approaches reveal how learning suppresses the microRNA system to trigger de novo synthesis of plasticity proteins, a missing link in the current model of microRNA-mediated translation in persistent synaptic plasticity and memory.
Motile interstitial T cells in live zebrafish access a broad range of length-scales due to long-lived cell-intrinsic variation in speed, and a coupling between speed and directional persistence.