2,221 results found
    1. Neuroscience

    A neural circuit for flexible control of persistent behavioral states

    Ni Ji, Gurrein K Madan ... Steven W Flavell
    Circuit-wide calcium imaging during C. elegans foraging elucidates the functional architecture of a neural circuit controlling the choice between two alternative behavioral states.
    1. Genetics and Genomics
    2. Neuroscience

    A persistent behavioral state enables sustained predation of humans by mosquitoes

    Trevor R Sorrells, Anjali Pandey ... Leslie B Vosshall
    Brief fictive carbon dioxide sensation induced by optogenetics in the female mosquito induces long-lasting arousal and probing, explaining the persistent predatory behavior of this dangerous disease-vectoring insect.
    1. Neuroscience

    P1 interneurons promote a persistent internal state that enhances inter-male aggression in Drosophila

    Eric D Hoopfer, Yonil Jung ... David J Anderson
    A sexually dimorphic circuit node controls a persistent, internal state that promotes fighting and mating in Drosophila, revealing parallels with mammalian systems suggestive of a conserved circuit "motif" controlling social behaviors.
    1. Neuroscience

    The neural basis for a persistent internal state in Drosophila females

    David Deutsch, Diego Pacheco ... Mala Murthy
    A set of sexually dimorphic neurons in female flies is part of a recurrent neural network and drives minutes-long persistent neural activity and persistent social behaviors.
    1. Neuroscience

    Brain states govern the spatio-temporal dynamics of resting-state functional connectivity

    Felipe Aedo-Jury, Miriam Schwalm ... Albrecht Stroh
    Distinct brain states govern resting state functional architecture revealed by neurophysiologically defined simultaneous optic-fiber-based calcium recordings and task-free functional magnetic resonance imaging (fMRI) in rats.
    1. Neuroscience

    Corollary discharge promotes a sustained motor state in a neural circuit for navigation

    Ni Ji, Vivek Venkatachalam ... Aravinthan DT Samuel
    A primary sensory interneuron in the thermotaxis circuit of C. elegans integrates sensory input and corollary discharge to drive persistent navigational states and movement towards preferred environments.
    1. Physics of Living Systems

    Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state

    Alexei V Tkachenko, Sergei Maslov ... Nigel Goldenfeld
    Time-varying heterogeneous social activity explains transient suppression of epidemic waves followed by long plateaus and eventual transition towards the endemic state of an emergent pathogen, such as COVID-19.
    1. Neuroscience

    Intrinsic mechanisms in the gating of resurgent Na+ currents

    Joseph L Ransdell, Jonathan D Moreno ... Jeanne M Nerbonne
    Experimental and modeling results reveal that the activation of resurgent sodium currents relies on the recovery of inactivated channels into a conducting state, and that the decay of resurgent currents reflects the accumulation of these channels into a slow-inactivated state.
    1. Neuroscience

    Cell type-specific contributions to a persistent aggressive internal state in female Drosophila

    Hui Chiu, Alice A. Robie ... Catherine E. Schretter
    Revised
    Reviewed Preprint v2
    Updated
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Lis1 regulates dynein by sterically blocking its mechanochemical cycle

    Katerina Toropova, Sirui Zou ... Andres E Leschziner
    Structural and functional studies reveal how a ubiquitous regulator of dynein keeps the microtubule-based motor in a persistent track-bound state.

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