14 results found
    1. Medicine
    2. Neuroscience

    Presenting a sham treatment as personalised increases the placebo effect in a randomised controlled trial

    Dasha A Sandra, Jay A Olson ... Mathieu Roy
    A laboratory experiment provides the first evidence that framing a sham treatment as personalised to one's genetics and physiology increases its placebo effect on pain.
    1. Genetics and Genomics

    Can education be personalised using pupils’ genetic data?

    Tim T Morris, Neil M Davies, George Davey Smith
    Current polygenic scores for education do not provide accurate predictions of educational achievement above other data or at the individual level.
    1. Computational and Systems Biology

    Patient-specific Boolean models of signalling networks guide personalised treatments

    Arnau Montagud, Jonas Béal ... Laurence Calzone
    Tailoring Boolean models to 488 prostate cancer patients and 8 cell lines data allows for the experimentally validated personalisation of drug treatments.
    1. Ecology
    2. Microbiology and Infectious Disease

    Universal gut microbial relationships in the gut microbiome of wild baboons

    Kimberly E Roche, Johannes R Bjork ... Elizabeth A Archie
    In baboon gut microbiota, most pairwise correlations in bacterial abundances are weak and negative, and bacterial correlation patterns are largely shared across hosts, rather than personalized to each hosts.
    1. Ecology
    2. Microbiology and Infectious Disease

    Microbiome: Finding common connections

    Ma Francesca M Santiago, Aura Raulo
    Ecological associations among gut bacteria are largely consistent across hosts in a population of wild baboons.
    Version of Record
    Insight
    1. Medicine

    Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

    Corrado Sandini, Daniela Zöller ... Stephan Eliez
    A novel methodical approach aimed at improving translation of network analyses to psychopathology provides an intuitive representation of longitudinal clinical pathways between symptoms and can assist in predicting prognosis.
    1. Computational and Systems Biology
    2. Medicine

    Personalized computational heart models with T1-mapped fibrotic remodeling predict sudden death risk in patients with hypertrophic cardiomyopathy

    Ryan P O'Hara, Edem Binka ... Natalia A Trayanova
    Personalized virtual-heart technology for arrhythmia risk assessment could transform the management of hypertrophic cardiomyopathy patients, eliminating many unnecessary primary-prevention defibrillator deployments while ensuring patients at high risk for arrhythmia are adequately protected.
    1. Medicine

    Time to Eat - A Personalized Circadian Eating Schedule Leads to Weight Loss Without Calorie Restriction: A Randomized Controlled Trial

    Isabell Wilming, Jana Tuschewski ... Dominic Landgraf
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

    Courtney Tindle, MacKenzie Fuller ... Soumita Das
    An integrated stem cell-based disease modeling and computational approach demonstrates how proximal airway epithelium is critical for SARS-CoV-2 infectivity and distal alveolar cells are critical for simulating the host responses.

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