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    1. Developmental Biology
    2. Evolutionary Biology

    Origin of the mechanism of phenotypic plasticity in satyrid butterfly eyespots

    Shivam Bhardwaj, Lim Si-Hui Jolander ... Antonia Monteiro
    A gradual, step-wise, physiological/molecular response of eyespot size to temperature is a likely adaptation to seasonal variation experienced in the habitat of Bicyclusanynana butterflies.
    1. Evolutionary Biology

    Multifactorial processes underlie parallel opsin loss in neotropical bats

    Alexa Sadier, Kalina TJ Davies ... Karen E Sears
    Parallel losses of short-wave light sensitivity in diverse bats occurred through independent changes at multiple steps in the conversion of genotype into functional phenotype, including pre-, during, and post-transcription.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Reverse evolution leads to genotypic incompatibility despite functional and active site convergence

    Miriam Kaltenbach, Colin J Jackson ... Nobuhiko Tokuriki
    Enzyme evolution is reversible on a structural and functional (phenotypic) level, but through a different mutational pathway that leads to genotypic incompatibility with the ancestor.
    1. Evolutionary Biology

    Phenotypic plasticity as an adaptation to a functional trade-off

    Xiao Yi, Antony M Dean
    A plastic behavior in Escherichia coli is enabled by a single amino acid replacement in adaption to changing environments.
    1. Ecology
    2. Evolutionary Biology

    Complex plumages spur rapid color diversification in kingfishers (Aves: Alcedinidae)

    Chad M Eliason, Jenna M McCullough ... Michael J Andersen
    Treating color patterns in a geometric morphometrics framework reveals rapid rates of color evolution that are explained by a combination of intrinsic organismal features (color variation among patches) and geography within a cosmopolitan radiation of birds.
    1. Developmental Biology
    2. Evolutionary Biology

    Maternally regulated gastrulation as a source of variation contributing to cavefish forebrain evolution

    Jorge Torres-Paz, Julien Leclercq, Sylvie Rétaux
    Phenotypic evolution can originate from variations in very precocious developmental events, starting even before fecundation, during the fabrication of the egg in the mother's gonad.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

    Tracy M Smith, Madison A Youngblom ... Caitlin S Pepperell
    Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants

    Carlos Martinez-Ruiz, Rodrigo Pracana ... Yannick Wurm
    Analyses of allelic- and socially-biased gene expression reveal that suppressed recombination causes most of the expression differences in the social supergene, with only few differences due to socially antagonistic selection.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines

    Elliott D SoRelle, Joanne Dai ... Micah A Luftig
    Single-cell RNA sequencing highlights the influence of host–pathogen interactions and stochasticity on transcriptional and phenotypic variance in lymphoblastoid cell lines derived from Epstein–Barr virus-infected primary B cells.
    1. Developmental Biology
    2. Evolutionary Biology

    Cortex cis-regulatory switches establish scale colour identity and pattern diversity in Heliconius

    Luca Livraghi, Joseph J Hanly ... Chris D Jiggins
    The evolution of a butterfly mimetic phenotype is driven by modular cis-regulstory switches controlling a ‘hotspot’ gene.