For Drosophila melanogaster, the scent of alcohol—normally associated with preferred egg-laying sites—potentiates a male pheromone signal, thereby increasing the aggressive competition between males for the reproductive resource.
Molecular and cell biology analyses reveal novel roles of Polo-like kinases in establishing non-random segregation patterns of spindle-associated microtubule-organizing centers during mitosis, a phenomenon linked with replicative cell aging.
Caenorhabditis elegans homologs of carboxylesterases that localize to intestinal organelles orchestrate the assembly of modular signaling molecules from building blocks that integrate diverse metabolic pathways.
The sleep-courtship balance in Drosophila males is modulated by yeast/protein availability, and dopaminergic neurons projecting to the protocerebral bridge act downstream of courtship-regulating neurons for male sleep regulation.
LOV2GIVe allows to activate Gi proteins non-invasively with innocuous blue light based on a design principle unrelated to light-activated GPCRs (metazoan opsins), thereby expanding the range of potential experimental applications.