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    1. Cell Biology
    2. Physics of Living Systems

    Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice

    Kaushikaram Subramanian et al.
    Establishing retinal contrast transmission as a novel determinant of mammalian fitness, this research adds functional significance to a prominent exception of nuclear organization, previously described in nocturnal rod photoreceptor cells.
    1. Physics of Living Systems

    High-speed motility originates from cooperatively pushing and pulling flagella bundles in bilophotrichous bacteria

    Klaas Bente et al.
    Bacteria reach swimming speeds of several hundred body lengths per second and change direction in less than 5 ms by using coordinated flagella bundle agitation.
    1. Cell Biology
    2. Neuroscience

    Neurotrophins induce fission of mitochondria along embryonic sensory axons

    Lorena Armijo-Weingart et al.
    Induction of the fission of mitochondria-populating sensory axons is shown to be a novel biological action of neurotrophins.
    1. Structural Biology and Molecular Biophysics

    Architectural principles for Hfq/Crc-mediated regulation of gene expression

    Xue Yuan Pei et al.
    Structural insights show how RNA chaperones cooperate to recognise defined target transcripts and suppress gene expression.
    1. Computational and Systems Biology
    2. Neuroscience

    Bumblebee visual allometry results in locally improved resolution and globally improved sensitivity

    Gavin J Taylor et al.
    Bigger bumblebee eyes have better vision, yet their field of view, sensitivity, and resolution do not all simply scale up with eye size, being improved locally instead.
    1. Neuroscience

    Ventrolateral periaqueductal gray neurons prioritize threat probability over fear output

    Kristina M Wright, Michael A McDannald
    Single-unit activity in the ventrolateral periaqueductal gray, a brain region implicated in organizing fear output, is found to reflect threat probability, a more versatile threat signal.
    1. Neuroscience

    Functionally defined white matter of the macaque monkey brain reveals a dorso-ventral attention network

    Ilaria Sani et al.
    Primate attention is not limited to a dorsal fronto-parietal network, but includes a ventral temporal node and its dorso-ventral interactions with other attentional areas.
    1. Plant Biology

    A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis

    Naoki Takahashi et al.
    Arabidopsis deploys the core signalling module that perceives distinct stress signals, such as DNA damage and heat stresses, and represses G2/M-specific genes, thereby causing cell cycle arrest.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

    Mark E Lush et al.
    Several support cell populations balance progenitor maintenance with differentiation in zebrafish lateral line sensory organs.
    1. Cancer Biology
    2. Cell Biology

    Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

    Giulia Bertolin et al.
    AurkA is imported into mitochondria at interphase, and it induces organelle elongation and enhances ATP production when over-expressed.