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Hypoxia does not increase glycolysis in proliferating primary cells and antagonizes the increase in glycolysis caused by activation of hypoxia-inducible factor in normoxia, in part, through activation of MYC signaling pathways.

A signal for inflammatory cell death is induced by the disruption of cellular metabolism.

TIGAR deficiency in cholinergic neuron enhanced intracellular acetyl-CoA levels and pyruvate dehydrogenase flux into the TCA cycle that drives increased cholinergic tone with reduced heart rate and blood pressure and raised resistance against the paralytic curare and cold-induced hypothermia.

A method to profile hair pigmentation patterns establishes a new approach for psychobiological studies and links metabolic changes to greying in humans.

Glycolysis is locally enhanced and redirected in zebrafish to generate lactate, which functions as a signaling molecule to fully activate Fgf target genes required for proper sensory and neural development.

TRIM32-mediated glycolytic flux generates precursors that are utilized for biomass production in non-dividing muscle, brain and tumor cells, demonstrating a universal metabolic function for TRIM32 in cell growth.

The specific metabolic pathways that increase neuron regeneration in ogt-1 mutant C. elegans following in vivo laser axotomy, highlighting the potential power for such metabolic targets in the treatment of neuronal injury.

The circadian clock of Synechococcus elongatus PCC7942 schedules the activity of the transcription factor RpaA, which controls key events in carbon metabolism that contribute to cell fitness in conditions mimicking the natural environment.

A high-throughput phenotypic human sperm screening platform was developed which allows for major drug discovery programmes for male contraception.