243 results found
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

    Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

    Liza Dahal, Thomas GW Graham ... Xavier Darzacq
    Type II nuclear receptors do not always compete for a limiting pool of their obligate partner RXRa.
    1. Microbiology and Infectious Disease

    Virus adaptation to heparan sulfate comes with capsid stability tradeoff

    Han Kang Tee, Simon Crouzet ... Caroline Tapparel
    Enterovirus A71 adaptation to bind heparan sulfate as receptor comes with compensation that destabilizes its virus capsid.
    1. Neuroscience

    Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior

    Alex J Yonk, Ivan Linares-García ... David J Margolis
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Sigh generation in preBötzinger Complex

    Yan Cui, Evgeny Bondarenko ... Jack L Feldman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Midbrain encodes sound detection behavior without auditory cortex

    Tai-Ying Lee, Yves Weissenberger ... Johannes C Dahmen
    Behavior is a major determinant of the activity of auditory midbrain neurons and can shape their responses independently of input from the auditory cortex.
    1. Neuroscience

    Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling

    Benjamin Le Gac, Marine Tournissac ... Bruno Cauli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances

    Jian Qiu, Margaritis Voliotis ... Martin J Kelly
    Kiss1ARH neurons transition from synchronous to burst firing under preovulatory levels of E2, causing a shift from peptidergic to glutamatergic transmission that drives the GnRH surge through enhanced glutamate neurotransmission.
    1. Cell Biology
    2. Physics of Living Systems

    Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum

    Pyae Hein Htet, Edward Avezov, Eric Lauga
    The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.

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