22 results found
    1. Evolutionary Biology
    2. Plant Biology

    Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes

    Glen Wheeler et al.
    Genomic evidence suggests that L-gulonolactone oxidase-the terminal enzyme in vitamin C synthesis, which has been repeatedly lost throughout animal evolution-was lost in plants and other photosynthetic eukaryotes following plastid acquisition.
    1. Neuroscience

    Cortex commands the performance of skilled movement

    Jian-Zhong Guo et al.
    Optogenetic inhibition demonstrates that the cortex is necessary and sufficient for the initiation and execution of a learned, skilled action.
    1. Plant Biology

    PCH1 integrates circadian and light-signaling pathways to control photoperiod-responsive growth in Arabidopsis

    He Huang et al.
    A conserved, circadian-regulated protein alters light perception in plants to regulate daily growth in response to changing photoperiod.
    1. Neuroscience

    Neural coding in barrel cortex during whisker-guided locomotion

    Nicholas James Sofroniew et al.
    A tactile virtual reality system reveals the neural codes in the barrel cortex that underlie wall-tracking in mice.
    1. Neuroscience

    Distinct roles of visual, parietal, and frontal motor cortices in memory-guided sensorimotor decisions

    Michael J Goard et al.
    Visual, parietal, and frontal motor cortices play distinct and necessary roles in mapping sensory features to future motor action.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Limitations to photosynthesis by proton motive force-induced photosystem II photodamage

    Geoffry A Davis et al.
    Storage of solar energy in the thylakoid electrical field by photosynthesis in vivo can substantially destabilize charge-separated states in photosystem II, leading to singlet oxygen production and photodamage, contributing to loss of productivity, especially under fluctuating light experienced in the field.
    1. Neuroscience

    Optocontrol of glutamate receptor activity by single side-chain photoisomerization

    Viktoria Klippenstein et al.
    Introduction of single photoswitchable unnatural amino acid into a neuronal receptor provides reversible, rapid and robust control of its activity by light, representing an important contribution to the fast expanding field of optopharmacology.
    1. Neuroscience

    An inhibitory gate for state transition in cortex

    Stefano Zucca et al.
    Two major subtypes of cortical interneurons, the PV and the SST positive cells, causally contribute to the regulation of large-scale state transitions in the cortex.
    1. Neuroscience

    Causal role for the subthalamic nucleus in interrupting behavior

    Kathryn H Fife et al.
    Activation of the subthalamic nucleus (STN) pauses or disrupts behavior, while STN inhibition reduces the disruptive effects of surprise, indicating that STN activation is both sufficient and necessary for behavioral inhibition.
    1. Neuroscience

    Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior

    Justin K O'Hare et al.
    Fast-spiking interneurons of the dorsolateral striatum are found to provide a microcircuit mechanism driving the circuit properties and behavioral adaptations that characterize habit.

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