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    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    The structure of photosystem I from a high-light-tolerant cyanobacteria

    Zachary Dobson, Safa Ahad ... Yuval Mazor
    The necessity of studying extremophile organisms is exemplified by the structure of photosystem I from a high-light tolerant cyanobacteria, demonstrating the relationship between the structure and function in photosystem I.
    1. Genetics and Genomics

    miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

    Isabelle Schiffer, Birgit Gerisch ... Adam Antebi
    Coordinate control of lysosomal v-ATPase subunits and biogenesis factor TFEB by miR-1 identifies a key regulatory axis with strong links to age-related proteotoxic disease.
    1. Plant Biology

    A multifaceted analysis reveals two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis

    Rosa Pipitone, Simona Eicke ... Emilie Demarsy
    Serial-Block-Face Scanning Electron Microscopy (SBF-SEM) associated with biomolecular analysis show that chloroplast differentiation proceeds by distinct ‘structure establishment’ and ‘chloroplast proliferation’ phases, each with differential protein and lipid regulation.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Identification of distinct pH- and zeaxanthin-dependent quenching in LHCSR3 from Chlamydomonas reinhardtii

    Julianne M Troiano, Federico Perozeni ... Gabriela S Schlau-Cohen
    Light-harvesting complex stress-related is a protein from photosynthetic green algae that prevents damage from sunlight via two distinct conformational processes, which protect against different timescales of solar fluctuations.
    1. Plant Biology

    Altered N-glycan composition impacts flagella-mediated adhesion in Chlamydomonas reinhardtii

    Nannan Xu, Anne Oltmanns ... Michael Hippler
    Adhesion force measurements reveal that proper N-glycosylation of flagellar membrane proteins is crucial for adhering C. reinhardtii cells onto surfaces.
    1. Cell Biology
    2. Plant Biology

    Photosynthetic sea slugs induce protective changes to the light reactions of the chloroplasts they steal from algae

    Vesa Havurinne, Esa Tyystjärvi
    Slug chloroplasts avoid damage to photosynthesis by maintaining an oxidized electron transfer chain with the help of oxygen-sensitive electron acceptors.
    1. Plant Biology

    Photosynthesis without β-carotene

    Pengqi Xu, Volha U Chukhutsina ... Roberta Croce
    Tobacco plants containing xanthophyll astaxanthin show that both photosystems are fully functional in the absence of carotenes, and these pigments are not essential for photosynthesis.
    1. Cancer Biology

    The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

    Jaime N Wertman, Nicole Melong ... Jason N Berman
    L-mimosine and dopamine protect against cisplatin-induced oto- and nephrotoxicity in zebrafish and human cell line models.
    1. Plant Biology

    A cis-carotene derived apocarotenoid regulates etioplast and chloroplast development

    Christopher I Cazzonelli, Xin Hou ... Barry J Pogson
    Carotenoids are not just required as core components for plastid biogenesis, they can be cleaved into an apocarotenoid signal that regulates etioplast and chloroplast development during extended periods of darkness.
    1. Cell Biology
    2. Genetics and Genomics

    The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response

    Karina Perlaza, Hannah Toutkoushian ... Silvia Ramundo
    A genetic screen in a unicellular photosynthetic organism uncovers the first essential signaling component in the chloroplast unfolded protein response that relays information from the chloroplast to the nuclear compartment.