313 results found
    1. Cell Biology

    Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1

    Ling Luo et al.
    The eye produces a protein that inhibits the growth of blood vessels in the deep retina, which includes the photoreceptor layer, and disruption of this process can lead to blindness.
    1. Neuroscience

    A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse

    J Wesley Maddox et al.
    Ca2+ influx through Cav1.4 channels is required for the structural, but not the molecular organization of the rod photoreceptor synapse.
    1. Developmental Biology
    2. Neuroscience

    R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners

    Jessica Douthit et al.
    R7 photoreceptors require the endosomal protein Lost and Found to form stable connections only when this protein is also present in neurons that are synaptic partners of R7.
    1. Neuroscience

    Ciliary and rhabdomeric photoreceptor-cell circuits form a spectral depth gauge in marine zooplankton

    Csaba Verasztó et al.
    In a zooplankton larva, ciliary and rhabdomeric photoreceptor cells work antagonistically to form a spectral depth gauge.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Natural variation in stochastic photoreceptor specification and color preference in Drosophila

    Caitlin Anderson et al.
    Binding site affinity and transcription factor levels are finely tuned in nature to regulate stochastic expression, setting the ratio of alternative photoreceptor fates and determining color preference.
    1. Genetics and Genomics

    Differing isoforms of the cobalamin binding photoreceptor AerR oppositely regulate photosystem expression

    Haruki Yamamoto et al.
    A novel B12 containing photoreceptor is synthesized as two different isoforms that interact with the same transcription factor, with one isoform directing activation and the other promoting repression of photosystem synthesis.
    1. Developmental Biology
    2. Evolutionary Biology

    Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment

    Kate A Rawlinson et al.
    A new opsin receptor is light-sensitive and expressed in a unique type of photoreceptor in a flatworm that encloses over 400 sensory cilia within its cell membrane.
    1. Genetics and Genomics
    2. Neuroscience

    Co-expression of xenopsin and rhabdomeric opsin in photoreceptors bearing microvilli and cilia

    Oliver Vöcking et al.
    The recently characterized opsin group of xenopsins is likely a major player in animal eye evolution and may have been present in an ancient, highly plastic eye photoreceptor cell type.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Cis-regulatory basis of sister cell type divergence in the vertebrate retina

    Daniel P Murphy et al.
    While photoreceptor and bipolar cells exhibit very similar cis-regulatory grammars, subtle differences in homeodomain motif enrichment represent a key distinction driving the divergence in their transcriptomes.
    1. Developmental Biology
    2. Neuroscience

    Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance

    Hiroki Takechi et al.
    Timely regulation of growth cone dynamics, including filopodial and cytoskeletal rearrangements through phosphorylation signals from glial cells, shapes the photoreceptor axon targeting.

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