163 results found
    1. Neuroscience

    Receptive field center-surround interactions mediate context-dependent spatial contrast encoding in the retina

    Maxwell H Turner et al.
    In the retina, the receptive field surround preserves the spatial contrast sensitivity of the center in the face of naturalistic changes in local luminance.
    1. Developmental Biology

    Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate

    Ilya Chuykin et al.
    Par3 is polarized in the plane of the vertebrate neural plate, binds and recruits Prickle3 to the apical membrane and promotes the formation of core planar cell polarity complexes.
    1. Developmental Biology
    2. Neuroscience

    Ordered arrangement of dendrites within a C. elegans sensory nerve bundle

    Zhiqi Candice Yip, Maxwell G Heiman
    A nerve bundle is not simply a cable of wires, but has order within it.
    1. Cell Biology

    Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles

    Garrett A Greenan et al.
    Cryo-electron tomography of mammalian and fly centrioles shows that the ninefold symmetry of centrioles is set by species-specific microtubule linkers.
    1. Microbiology and Infectious Disease

    Robust manipulation of the behavior of Drosophila melanogaster by a fungal pathogen in the laboratory

    Carolyn Elya et al.
    A newly described isolate of the behavior-manipulating fly pathogen Entomophthora muscae that naturally infects fruit flies can be cultured in the lab, enabling molecular investigation of how microbes induce behavior changes in animal hosts.
    1. Cell Biology
    2. Neuroscience

    Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration

    Andrew T Moehlman et al.
    Tuning of BiP activity by Fic-mediated AMPylation is required for Drosophila photoreceptor plasticity and attenuation of the unfolded protein response.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells

    Raghuvir Viswanatha et al.
    Pooled CRISPR knockout screening in Drosophila cells enables high-resolution, genome-wide functional genomic comparisons in cell-lines across vast evolutionary distance.
    1. Plant Biology

    Shade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis

    Xu Huang et al.
    A phosphorylation dependent translocation of PIF7 and involvement of 14-3-3 proteins reveal novel regulation mechanisms in shade signal transduction.

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