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    1. Neuroscience

    The carcinine transporter CarT is required in Drosophila photoreceptor neurons to sustain histamine recycling

    Drew Stenesen et al.
    Fly vision depends on a member of the SLC22 transporter family for recycling the histamine neurotransmitter following its uptake by glia and its modification into the transport metabolite carcinine.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Complementary shifts in photoreceptor spectral tuning unlock the full adaptive potential of ultraviolet vision in birds

    Matthew B Toomey et al.
    Birds that see ultraviolet light tune the sensitivity of their short-wavelength photoreceptors with colored filters to maximize the number of colors they can see.
    1. Developmental Biology

    Parallel Activin and BMP signaling coordinates R7/R8 photoreceptor subtype pairing in the stochastic Drosophila retina

    Brent S Wells et al.
    TGFβ family members instruct a cell fate decision downstream of stochastic signaling in the Drosophila retina to ensure correct pairing between different color photoreceptors for color vision.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

    Budd A Tucker et al.
    Skin cells from a patient with retinitis pigmentosa have been used to generate induced pluripotent stem cells, which could potentially form the basis of new treatments for this disease.
    1. Genetics and Genomics
    2. Neuroscience

    Evolution: The enigmatic xenopsins

    Detlev Arendt
    A new member of the family of light-sensitive proteins called opsins has stirred up our view of photoreceptors.
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    1. Neuroscience

    Guanylate cyclase 1 relies on rhodopsin for intracellular stability and ciliary trafficking

    Jillian N Pearring et al.
    Rather than relying on intrinsic intracellular targeting information, the key phototransduction enzyme guanylate cyclase 1 is delivered to the photosensory cilium with the visual pigment rhodopsin.
    1. Neuroscience

    A Cambrian origin for vertebrate rods

    Sabrina Asteriti et al.
    Several key functional features of jawed vertebrate rods are also present in lamprey photoreceptors, indicating that our Cambrian ancestors possessed dim light vision.
    1. Computational and Systems Biology
    2. Neuroscience

    Connectivity map of bipolar cells and photoreceptors in the mouse retina

    Christian Behrens et al.
    A quantitative analysis of the connectivity between photoreceptors and bipolar cells in the mouse retina based on electron microscopy data yields exceptions from established rules of outer retinal connectivity.
    1. Computational and Systems Biology
    2. Developmental Biology

    Tuned polymerization of the transcription factor Yan limits off-DNA sequestration to confer context-specific repression

    C Matthew Hope et al.
    Tuned protein–protein interaction affinity optimizes the repressive function of the ETS family transcription factor Yan in order to contribute specificity and robustness to cell fate specification in the developing Drosophila eye.
    1. Neuroscience

    Mouse rods signal through gap junctions with cones

    Sabrina Asteriti et al.
    Electrophysiological recordings show that cones in the eyes of mice are able to receive strong input from rods via gap junctions, supporting the view that this route plays an important role in vision.