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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration

    Stephanie L Tsai et al.
    Elucidation of the molecular basis of early wound epidermis dependence during salamander limb regeneration reveals midkine as a key modulator of wound epidermis development and wound-healing resolution.
    1. Evolutionary Biology

    The structure of species discrimination signals across a primate radiation

    Sandra Winters et al.
    Machine learning and experimental tests of receiver bias identify signal components critical to correct species classification in guenons, linking face pattern diversity to selection for species discrimination.
    1. Developmental Biology
    2. Neuroscience

    A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

    Weidong Feng et al.
    A molecular mechanism that involves highly conserved transcription factors enables cholinergic motor neurons of the nematode Caenorhabditis elegans to become and remain functional.
    1. Neuroscience

    The computation of directional selectivity in the Drosophila OFF motion pathway

    Eyal Gruntman et al.
    ON and OFF visual motion is computed with the same algorithm despite differences in circuit architecture.
    1. Evolutionary Biology

    Retinal oxygen supply shaped the functional evolution of the vertebrate eye

    Christian Damsgaard et al.
    Multiple respiratory and vascular mechanisms have recurrently evolved across the vertebrates to alleviate the oxygen diffusion limitations inherent to the morphology of the retina.
    1. Genetics and Genomics
    2. Neuroscience

    Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation

    Ryoji Amamoto et al.
    Probe-Seq is a cell type specific bulk RNA sequencing method that can be applied to a wide-ranging tissue types from both vertebrates and invertebrates without genetic labeling.
    1. Neuroscience

    Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing

    Lauren E Foley et al.
    A screen targeting RNA-associated proteins reveals that PSI regulates timeless alternative splicing and thus controls the period of Drosophila circadian behavior and its phase under temperature cycles.
    1. Neuroscience

    Asymmetric ON-OFF processing of visual motion cancels variability induced by the structure of natural scenes

    Juyue Chen et al.
    The fruit fly estimates visual motion by incorporating ON-OFF asymmetric processing that only improves performance when stimuli have light-dark asymmetries matched to natural scenes.
    1. Cell Biology

    Crumbs organizes the transport machinery by regulating apical levels of PI(4,5)P2 in Drosophila

    Johanna Lattner et al.
    The polarity protein crumbs controls apical secretion and the architecture of the apical domain by modulating PI(4,5)P2 levels and the organization of apical Rab6-, Rab11-, and Rab30-dependent trafficking.
    1. Neuroscience

    Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits

    Kaushiki P Menon et al.
    The survival of Drosophila amacrine neurons is controlled by neurotrophic signaling mediated by interactions between the cell surface protein DIP-γ and its partner Dpr11, which is expressed on presynaptic photoreceptors.