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    1. Evolutionary Biology

    Evolutionary footprints of a cold relic in a rapidly warming world

    Eva Wolf, Emmanuel Gaquerel ... Marcus A Koch
    Evolutionary dynamics of polyploid plants of the genus Cochlearia during past periods of rapid climate change indicate increased rates of speciation and diversification in response to pronounced glacial cycles and cold periods in particular.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Genomic epidemiology of the first two waves of SARS-CoV-2 in Canada

    Angela McLaughlin, Vincent Montoya ... Jeffrey B Joy
    Canadian COVID-19 travel restrictions imposed in March 2020 greatly reduced SARS-CoV-2 importations, but were insufficient to prevent new sublineages of similar transmissibility from being introduced and replacing early sublineages.
    1. Evolutionary Biology

    The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    The evolutionary trajectory of phytophagous weevils reveals how ancient host plant shifts and continental drift influenced the development of diverse insect-plant interactions through time.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Radiocarbon and genomic evidence for the survival of Equus Sussemionus until the late Holocene

    Dawei Cai, Siqi Zhu ... Yu Jiang
    The first nuclear genomes of the Equus (Sussemionus) ovodovi enable us to reconstruct the speciation and extinction trajectory of this lineage.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Insight into the evolution of microbial metabolism from the deep-branching bacterium, Thermovibrio ammonificans

    Donato Giovannelli, Stefan M Sievert ... Costantino Vetriani
    The genome of Thermovibrio ammonificans encodes ancestral pathways (e.g., hydrogen oxidation) and more recently acquired ones (e.g., nitrate reduction) and a hybrid pathway for CO2 fixation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The whale shark genome reveals patterns of vertebrate gene family evolution

    Milton Tan, Anthony K Redmond ... Timothy Read
    The new whale shark genome assembly represents the best gapless chondrichthyan genome assembly yet, and comparative genomic analyses provide insights into the evolution of vertebrate genome origins, immunity, and gigantism.
    1. Cell Biology

    Endosymbiotic selective pressure at the origin of eukaryotic cell biology

    Parth K Raval, Sriram G Garg, Sven B Gould
    All the characteristic traits of the eukaryotic cell, the basic unit of all macroscopic life, commenced to originate in a prokaryote as means to serve an endosymbiont today known as mitochondria.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Molecular evidence of hybridization between pig and human Ascaris indicates an interbred species complex infecting humans

    Alice Easton, Shenghan Gao ... Thomas B Nutman
    Comparative phylogenomic analyses based on a new reference-quality human Ascaris genome assembly reveals a pig/human interbred species complex with implications for Ascaris control worldwide.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Unifying the known and unknown microbial coding sequence space

    Chiara Vanni, Matthew S Schechter ... Antonio Fernàndez-Guerra
    A newly developed computational framework provides an overview of the extent, diversity, and relevance of the genes of unknown function in genomes and metagenomes.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Parallel evolution between genomic segments of seasonal human influenza viruses reveals RNA-RNA relationships

    Jennifer E Jones, Valerie Le Sage ... Seema S Lakdawala
    Phylogenetic relationships between viral RNA segments are distinct between subtypes and lineages of seasonal human influenza A viruses and implicate RNA-RNA relationships as novel drivers of influenza virus evolution.