151 results found
    1. Computational and Systems Biology

    Efficient coding in biophysically realistic excitatory-inhibitory spiking networks

    Veronika Koren, Simone Blanco Malerba ... Stefano Panzeri
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Glia control experience-dependent plasticity in an olfactory critical period

    Hans C Leier, Alexander J Foden ... Heather T Broihier
    A Drosophila olfactory circuit exhibits experience-dependent glial pruning during a well-defined critical period, with long-term consequences for odor processing.
    1. Neuroscience

    Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm

    Scott Isherwood, Sarah A Kemp ... Birte Forstmann
    A novel meta-analytical method aggregating five SST datasets does not find evidence for the innervation of the hyperdirect or indirect cortico-basal-ganglia pathways in successful response inhibition.
    1. Computational and Systems Biology
    2. Neuroscience

    Multisensory integration operates on correlated input from unimodal transient channels

    Cesare V Parise, Marc O Ernst
    Psychophysical experiments and computational modeling demonstrate the importance of transient, instead of sustained, channels for the integration of audiovisual signals.
    1. Computational and Systems Biology

    Emergence of power law distributions in protein-protein interaction networks through study bias

    David B Blumenthal, Marta Lucchetta ... Martin H Schaefer
    Biased research interest in proteins and aggregation of interactions from multiple studies can explain why node degree distributions in protein-protein interaction networks follow a power law.
    1. Neuroscience
    2. Computational and Systems Biology

    Active dendrites enable robust spiking computations despite timing jitter

    Thomas SJ Burger, Michael E Rule, Timothy O’Leary
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    A neuronal least-action principle for real-time learning in cortical circuits

    Walter Senn, Dominik Dold ... Mihai A Petrovici
    A principle from which the neuronal dynamics and synaptic plasticity in arbitrary network architectures can be inferred, so that output errors are online minimized while simultaneously processing sensory input streams.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Harnessing AlphaFold to reveal hERG channel conformational state secrets

    Khoa Ngo, Pei-Chi Yang ... Igor Vorobyov
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks

    Han Lu, Sandra Diaz ... Andreas Vlachos
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum

    Pyae Hein Htet, Edward Avezov, Eric Lauga
    The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.

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