1,194 results found
    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome

    Melinda S Modrell et al.
    An unbiased transcriptomic approach reveals that developing paddlefish electrosensory organs express genes essential for mechanosensory hair cell development and synaptic transmission, and identifies candidates for mediating electroreceptor development and function.
    1. Microbiology and Infectious Disease

    Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

    Saurabh Mishra et al.
    Intrinsic tolerance of Mycobacterium tuberculosis toward the world's most successful antibacterials, β-lactams, is dependent on cytoplasmic redox potential and an intracellular redox-sensor WhiB4.
    1. Cell Biology
    2. Neuroscience

    Social communication of predator-induced changes in Drosophila behavior and germ line physiology

    Balint Z Kacsoh et al.
    Reproductive behavior is conferred from experienced to naïve Drosophila as a behavioral social strategy allowing naïve groups to anticipate a threat from a predator.
    1. Plant Biology

    ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology

    Valentina De Col et al.
    The monitoring of ATP dynamics in living plants using fluorescent protein biosensor provides evidence for the complex relationship between cellular energy status and growth.
    1. Computational and Systems Biology
    2. Neuroscience

    Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

    Sunitha Rangaraju et al.
    A transcriptome-based metric for aging reveals a longevity mechanism that specifically prolongs the duration of young adulthood rather than slowing overall aging.
    1. Ecology

    Cyclic bouts of extreme bradycardia counteract the high metabolism of frugivorous bats

    M Teague O'Mara et al.
    Novel heart rate strategies that minimize energy expenditure during the day are necessary to cope with high energy nocturnal lifestyles of tent-making bats.
    1. Neuroscience

    Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

    Nicole Scholz et al.
    Metabotropic mechanosensing occurs through an adhesion-type G protein-coupled receptor.
    1. Human Biology and Medicine

    Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

    Lauran Madden et al.
    A novel bioengineered human skeletal muscle model with accurate physiological and pharmacological responses may provide a useful tool for preclinical testing.
    1. Cell Biology

    Age-dependent diastolic heart failure in an in vivo Drosophila model

    Matthew P Klassen et al.
    As in humans, Drosophila hearts are able to maintain contractile performance during healthy aging, but this maintenance is associated with an increased susceptibility to progressive dysrhythmias that can lead to fibrillatory arrest.
    1. Cell Biology
    2. Neuroscience

    Piezo1 links mechanical forces to red blood cell volume

    Stuart M Cahalan et al.
    In red blood cells, the Piezo1 protein is responsible for sensing mechanical forces and volume regulation.

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