2,705 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    The cis-regulatory effects of modern human-specific variants

    Carly V Weiss et al.
    A genome-wide catalog of the regulatory effects of variants that separate modern humans from archaic humans.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA

    Zachary F Mandell et al.
    The general transcription elongation factor NusG functions as an intrinsic termination factor in Bacillus subtilis and together with NusA coordinates global gene expression including the motility regulon.
    1. Immunology and Inflammation

    Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages

    Carolin Ulbricht et al.
    Heterogeneity in cytoplasmic calcium concentration alongside B cell activation and differentiation is measured intravitally using an interdisciplinary imaging approach and novel numerical analysis.
    1. Medicine
    2. Neuroscience

    Respiratory depression and analgesia by opioid drugs in freely behaving larval zebrafish

    Shenhab Zaig et al.
    Emerging approaches in larval zebrafish to identify safe opioid therapies without the side-effect of respiratory depression.
    1. Neuroscience

    Egr2 induction in spiny projection neurons of the ventrolateral striatum contributes to cocaine place preference in mice

    Diptendu Mukherjee et al.
    The ventrolateral striatum is found to be recruited during the encoding of cocaine preference, within which Egr2-expressing ensembles are functionally important, as is the expression of Egr2 within them.
    1. Microbiology and Infectious Disease

    Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers

    Qing Yang et al.
    A quick and portable test makes saliva samples turn yellow when people are carrying SARS-CoV-2, the virus that causes COVID-19.
    1. Neuroscience

    Analysis of ultrasonic vocalizations from mice using computer vision and machine learning

    Antonio HO Fonseca et al.
    An open-source tool based on computational vision and machine learning shows high accuracy and sensitivity in the analysis of ultrasonic vocalizations.

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