Isabella V Soluri, Lauren M Zumerling ... Shelby A Blythe
Mechanisms for shaping the chromatin accessibility landscape operate during development to regulate how embryonic patterning information is interpreted at the level of gene regulatory networks.
Bradford M Stubenhaus, John P Dustin ... Jason Pellettieri
Physiological porphyrin biosynthesis causes photosensitivity in fasted planarians, providing an experimentally tractable animal model of acute porphyrias.
Marco Todesco, Natalia Bercovich ... Loren H Rieseberg
Variation in patterns of floral UV pigmentation is controlled by a single transcription factor in sunflower and affects both pollinator attraction and responses to environmental stresses.
Guy Wiedermann, Robert Alexander Bone ... J Kim Dale
Computational modelling together with experimental manipulation indicate that the stability and turnover of activated Notch is inextricably linked to the regulation of the pace of segmentation clock gene expression in the presomitic mesoderm.
Joseph M Chambers, Shahram Jevin Poureetezadi ... Rebecca A Wingert
The transcriptional coactivator ppargc1a regulates the renal progenitor patterning to delineate boundary formation of differentiated segment populations during nephrogenesis.
The spatial autocorrelation method Local Moran’s I was used for image segmentation to delineate pixel clusters representing congruous objects with fuzzy borders, in this case potassium ion channel clusters.
Laura Lleras Forero, Rachna Narayanan ... Stefan Schulte-Merker
In contrast to amniotes, zebrafish (ray-finned fish, teleost) centra are formed from specialised notochord sheath cells, and the segmental patterning of these cells is independent of the segmentation clock.
Paul Gerald Layague Sanchez, Victoria Mochulska ... Alexander Aulehla
A microfluidic experimental approach combined with dynamical systems theory reveals how to entrain an embryonic oscillator, the segmentation clock, and allows for the quantification of its entrainment properties.